Chronic urticaria: What diagnostic evaluation is best?
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A detailed history and 6-week trial of an H1 antihistamine are the best diagnostic evaluations for chronic urticaria. More extensive diagnostic work-up adds little, unless the patient's history specifically indicates a need for further evaluation (strength of recommendation: B, inconsistent or limited-quality evidence).
Journal of Family Practice, 60(10) 2011: 632a-632b.