Screening for gestational diabetes: Are there differences in outcomes using a cutoff of 130 or 140 mg/dL for the 1-hour glucose challenge test?
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When screening pregnant women for gestational diabetes with a 50-g, 1-hour oral glucose challenge test (OGCT), it is unclear if a cutoff of 130 or 140 mg/dL produces any difference in neonatal or maternal outcomes. Still, some experts recommend the lower cutoff in higher prevalence regions because of increased sensitivity (at the expense of specificity). Using a cutoff of 130 mg/dL, the OGCT is 79% sensitive and 87% specific, yielding (in a population with a prevalence of 2.6%) a positive predictive value of 14% and a negative predictive value of 99.4%.
Evidence-based practice 14, no. 10 (2011): 07