Screening for gestational diabetes: Are there differences in outcomes using a cutoff of 130 or 140 mg/dL for the 1-hour glucose challenge test?

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Screening for gestational diabetes: Are there differences in outcomes using a cutoff of 130 or 140 mg/dL for the 1-hour glucose challenge test?

Please use this identifier to cite or link to this item: http://hdl.handle.net/10355/11893

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Title: Screening for gestational diabetes: Are there differences in outcomes using a cutoff of 130 or 140 mg/dL for the 1-hour glucose challenge test?
Author: Jensen, Megan; Lozeau, Anne-Marie
Keywords: diagnostic accuracy
Date: 2011-10
Publisher: Family Physicians Inquiries Network
Citation: Evidence Based Practice 14(10): 07.
Abstract: When screening pregnant women for gestational diabetes with a 50-g, 1-hour oral glucose challenge test (OGCT), it is unclear if a cutoff of 130 or 140 mg/dL produces any difference in neonatal or maternal outcomes. Still, some experts recommend the lower cutoff in higher prevalence regions because of increased sensitivity (at the expense of specificity). Using a cutoff of 130 mg/dL, the OGCT is 79% sensitive and 87% specific, yielding (in a population with a prevalence of 2.6%) a positive predictive value of 14% and a negative predictive value of 99.4%.
URI: http://hdl.handle.net/10355/11893

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