Which UTI therapies are safe and effective during breastfeeding?

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Which UTI therapies are safe and effective during breastfeeding?

Please use this identifier to cite or link to this item: http://hdl.handle.net/10355/11904

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Title: Which UTI therapies are safe and effective during breastfeeding?
Author: Kaiser, Jessica; McPherson, Vanessa; Kaufmann, Leonora
Keywords: antibiotic penetration
Date: 2007-03
Publisher: Family Physicians Inquiries Network
Citation: Journal of Family Practice, 56(3) 2007: 225+.
Abstract: Trimethoprim/sulfamethoxazole (TMP/SM X) has a high success rate in eradicating bacteriuria for women with urinary tract infection and is compatible with breastfeeding (strength of recommendation: C, based on extrapolation from studies with nonlactating women and disease-oriented outcomes). Quinolones (ciprofloxacin, ofloxacin) are effective and probably compatible with breastfeeding; however, their use has not been recommended by many investigators based on arthropathy in animal studies (SOR: C, based on extrapolation from case series and disease-oriented outcomes). A 7-day course of nitrofurantoin has similar efficacy to TMP/SMX and is compatible with breastfeeding, but it should be avoided in populations at risk for glucose-6-phosphate dehydrogenase (G6PD) deficiency (also known as favism, most often found in patients of Mediterranean or African descent) (SOR: C, extrapolation from studies in nonlactating women and disease-oriented outcomes).
URI: http://hdl.handle.net/10355/11904

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