Secondary Causes of Obesity
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Secondary causes of obesity can be detected by obtaining a patient history and performing a physical examination. Laboratory testing is recommended when additional findings are present, such as dysmorphic features, short stature, slow growth velocity, delayed puberty, or clinical signs and symptoms of endocrine abnormalities (e.g., hirsutism, truncal obesity, violaceous striae). (Strength of recommendation [SOR]: C, based on expert opinion.) Underlying metabolic and genetic causes of obesity are uncommon. The small number of children with a secondary cause of obesity typically also have short stature. (SOR: C, based on a prospective cohort study.)
Clinical Inquiries, 2011 (MU)
American Family Physician, 83(8) 2011: -973.