Treatment of Recurrent Vulvovaginal Candidiasis
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A six-month treatment regimen with an antifungal agent decreases the recurrence of vulvovaginal candidiasis. (Strength of Recommendation [SOR]: A, based on good-quality randomized controlled trials [RCTs].) For women in mycologic remission, a six-month treatment regimen with an antifungal agent may result in an additional five to 10 months of clinical cure. (SOR: A, based on good-quality RCTs.) Suitable therapies include oral fluconazole (Diflucan; 150 mg once per week for six months) or oral itraconazole (Sporanox; 200 mg twice per day, one day per month for six months).
American Family Physician, 83(12) 2011: 1482-1484.