Nanomaterial surface modification for heat-transfer nanofluid and electrochemical DNA biosensor development
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[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Low-temperature plasma polymerization was performed to coat the individual nanomaterial not only for better suspension but also for thermal conductivity enhancement with water. With the increased hydrophilicity of nanomaterials surfaces, more stable nanomaterials-in-water suspension resulted in the anomalous thermal conductivity increase of fluid. Electrochemical DNA biosensor is the device to detect the DNA specifically related to the pathogenic microbes. A basic DNA biosensor is designed by the immobilization of a single-stranded oligonucleotide (probe) on a transducer surface to recognize its complementary (target) DNA sequence via hybridization. Cyclic voltammetry (CV) and direct pulse voltammetry (DPV) were used to measure the electrochemical response before and after target hybridization with two red-ox indicators, Ru(III) and Fe(III). Consequently, developed nanostructured microelectrode exhibited atto-molar sensitivity with complementary targets as well as an excellent specificity to non-complementary targets.
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