Antibody Testing for Systemic Lupus Erythematosus
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Antibody testing plays an important role when assessing patients, but should not be used alone to diagnose SLE. (Strength of Recommendation: C, based on expert opinion.) The antinuclear antibody (ANA) test is the most commonly used screening test for SLE. The presence of anti-DNA, anti-Sm, and antiphospholipid antibodies is more specific for diagnosing SLE.
Clinical Inquiries, 2011 (MU)
American Family Physician, 84(12) 2011: -1409.