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dc.contributor.authorOostendorp, Alisoneng
dc.contributor.authorLu, Yu, 1983-eng
dc.contributor.authorGallazzi, Fabioeng
dc.contributor.authorLever, John R. (John Riley), 1953-eng
dc.contributor.authorLever, Susan Z., 1952-eng
dc.contributor.corporatenameUniversity of Missouri-Columbia. Office of Undergraduate Researcheng
dc.contributor.meetingnameSummer Undergraduate Research and Creative Achievements Forum (2007 : University of Missouri--Columbia)eng
dc.date2007eng
dc.date.issued2007eng
dc.descriptionAbstract only availableeng
dc.description.abstractcritical step to obtain the necessary building block of the subsequent synthesis of the iodinated peptide. This was done by the use of the reagent bis(pyridine)iodonium tetrafluoroborate to add iodine to dimethyl tyrosine. Successful iodination of fmoc protected dimethyl tyrosine has been confirmed by 1HNMR, 13CNMR and Maldi-tof. The iodinated Dmt-D-Ala-Phe-Orn was prepared via solid phase synthesis. The protected amino acids were added in sequence from ornithine to I-dimethyl tyrosine to form the full peptide. The final product was successfully characterized via LCMS. The final peptide may be useful for targeting the brain's μ-opioid receptors.eng
dc.identifier.urihttp://hdl.handle.net/10355/1242eng
dc.languageen_USeng
dc.publisherUniversity of Missouri--Columbia. Office of Undergraduate Researcheng
dc.relation.ispartofcommunityUniversity of Missouri-Columbia. Office of Undergraduate Research. Undergraduate Research and Creative Achievements Forumeng
dc.source.urihttp://undergradresearch.missouri.edu/forums-conferences/abstracts/abstract-detail.php?abstractid=eng
dc.titleSolid phase synthesis of iodinated Dmt-D-Ala-Phe-Orn, a μ-opioid peptide [abstract]eng
dc.typePresentationeng


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