What should you tell pregnant women about exposure to parvovirus?
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Tell patients that parvovirus infections before 20 weeks' gestation confer a risk of fetal morbidity and mortality as high as 16%, but don't significantly increase long-term developmental sequelae (strength of recommendation [SOR]: B, prospective cohort studies). Parvovirus infection rates are similar in a variety of maternal workplace environments (SOR: A, prospective cohort studies); routinely excluding pregnant women from the workplace is unwarranted (SOR: C, expert opinion). Physicians should order immunologic assays for women who may have been exposed to parvovirus to assess maternal immunity and determine whether evaluation for fetal hydrops is necessary (SOR: C, expert opinion).
Clinical Inquiries, 2011 (MU)
Journal of Family Practice, 60(12) 2011: 765-766.