In male patients who suffer from idiopathic male infertility, does clomiphene improve fertility rates?
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In male patients with idiopathic infertility, clomiphene citrate alone has not been shown to be effective in improving fertility rates. (SOR: B, based on a single RCT.) Clomiphene and vitamin E together may improve male fertility and increase pregnancy rates. (SOR: C, based on a single small RCT.)
Evidence Based Practice 15(1): 14.