What is the differential diagnosis of elevated troponins in the absence of acute coronary syndrome?
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Elevated serum troponins are highly sensitive markers of myocardial necrosis. In the absence of acute coronary syndrome (ACS), troponin elevations are observed in heart failure, myocarditis, acute pulmonary embolism (PE), chronic obstructive pulmonary disease (COPD), sepsis, end-stage renal disease (ESRD), and cerebrovascular accidents.
Evidence Based Practice 15(1): 01-02.