Browsing College of Arts and Sciences (MU) by Thesis Advisor "Jurisson, Silvia S."
Now showing items 1-5 of 5
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Arsenic-72, 77 as a matched pair radiopharmaceutical for imaging and radiotherapy
(University of Missouri--Columbia, 2018)Radiopharmaceuticals deliver radionuclides to specific target sites via the bifunctional chelate approach, where the radionuclides are chelated with a ligand and linked to a targeting biomolecule. They can be categorized ... -
Production of high specific activity rhenium-186 for radiotherapeutic applications and reformulation of a novel liquid brachytherapy agent
(University of Missouri--Columbia, 2022)The continued development of methods for the production and separation of high specific activity (HSA) rhenium-186 (t1/2 = 90.64 h, Eb-ave = 359 keV (71 percent), 306 keV (22 percent)) would largely increase its use as a ... -
Synthesis and preclinical evaluation of peptide receptor-targeted diagnostic and therapeutic radiopharmaceuticals for prostate cancer
(University of Missouri--Columbia, 2019)The overexpression of certain peptide receptors on cancers cells can be exploited for the development of radiopharmaceuticals that are selectively delivered to cancer cells for diagnostic imaging or therapeutic purposes. ... -
Technetium and rhenium schiff base complexes for nuclear medicine
(University of Missouri--Columbia, 2019)This dissertation investigates the synthesis of rhenium and technetium Schiff base complexes for potential applications in nuclear medicine. In Chapter 2, a series of mixed ligand Re(III) complexes of the form trans-[Re( ... -
Trithiol ligand development for radioarsenic and radioantimony toward potential theranostic radiopharmaceutical agents
(University of Missouri--Columbia, 2022)Radiopharmaceuticals deliver radioactive drugs to specific target sites for imaging or therapy purposes, depending on the decay characteristics of the radionuclides. Potential radiopharmaceuticals are commonly designed via ...