What is the optimal interval for checking liver function tests (LFTs) in patients taking statins?
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Monitoring LFTs in asymptomatic patients taking statin medications is unlikely to provide clinical benefit, given the infrequency of statin-induced liver damage. New US Food and Drug Administration (FDA) prescribing information for all statins recommends monitoring at baseline and when clinically indicated. The American College of Cardiology/American Heart Association/National Heart, Lung, and Blood Institute (ACC/AHA/NHLBI) guidelines recommend monitoring at baseline, 12 weeks, and then annually for all statins. (SOR: C, based on expert opinion.)
Evidence Based Practice 15(3): 10.