Browsing 2012 UMKC Dissertations - Freely Available Online by Thesis Department "Cell Biology and Biophysics (UMKC)"
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Involvement of a specific ubiquitin ligase in the assembly of the dynein motor in the filamentous fungus Neurospora crassa
(University of Missouri--Kansas City, 2012-08-27)Eukaryotic cells utilize multiple molecular motor proteins to accomplish intracellular transport. The two microtubule based motors, kinesin and cytoplasmic dynein, work in concert to move cargoes outward and inward, ... -
A proteomic approach for studying LTR retrotransposon host factors in saccharomyces cerevisae
(University of Missouri--Kansas City, 2012-01-20)The Ty retrotransposons of S. cerevisiae are mobile elements that resemble retroviruses, both in their genetic structures and replication cycles. Ty retrotransposition begins in the nucleus with the transcription of Ty ... -
The role of drosophila protein kinase doubletime in circadian period determination, morning and evening oscillators and tauopathy
(University of Missouri--Kansas City, 2012-10-01)In this dissertation, I used the GAL4-UAS binary expression method to overexpress mutant and wild type forms of the circadian protein kinase DBT in order to address several basic questions about DBT's biological functions. ... -
Structure-function studies of the staphylococcal complement inhibitor protein family
(University of Missouri--Kansas City, 2012)Complement is a primary arm of innate immunity that plays essential roles in clearance of microbial invaders and immune complexes, initiation of inflammation, development, and differentiation and serves as a bridge to the ...