RSS 1.0Division of Biological Sciences (MU)
The Division of Biological Sciences at MU offers a unique integration of world-class research, award-winning graduate and undergraduate training, and outstanding community outreach. Our faculty research programs include the acquisition of new knowledge through basic research, and coordinated translational research to improve human health, our food supply, and our environment. Our graduate training programs emphasize the excitement of discovery and the development of individual creativity and critical reasoning skills, with graduate mentors who are experts at the frontiers of their field. In undergraduate education, as in our graduate programs, we emphasize the excitement of discovery and the development of individual creativity and critical reasoning skills, providing an excellent foundation for advanced study or direct entry into the workplace. Because science exposure in the pre-college years is critical to the development of both scientists and informed citizens, we also offer special outreach programs for secondary school science teachers and their students in Missouri.
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The role of heme oxygenase in metastatic melanoma tumorigenicity
(University of Missouri--Columbia, 2015)Reactive oxygen species (ROS) are highly reactive, tumorigenic molecules. In response to ROS accumulation, or oxidative stress, the transcription factor Nrf2 promotes expression by binding antioxidant response elements ... -
Therapeutic and chemopreventive potential of luteolin against growth and metastasis of breast cancer
(University of Missouri--Columbia, 2015)Breast cancer is the second leading cause of cancer-related death in older women. Many postmenopausal women undergo hormone replacement therapy (HRT) to alleviate the symptoms of menopause. Recent studies implicate the ... -
Changes in properties of lamprey reticulospinal neurons following spinal cord injury
(University of Missouri--Columbia, 2015)The lamprey is one of the most ancient vertebrates, sharing many of basic characteristics of the brain and spinal cord with higher, more evolved vertebrates such as mammals. However, unlike humans and other higher vertebrates, ... -
Unconventional oil and gas extraction as a novel source of endocrine disrupting chemicals to water and the potential for adverse human and animal health outcomes
(University of Missouri--Columbia, 2015)The proper and unimpeded function of hormones is essential for normal development, maturation, and prevention of chronic diseases. Endocrine disrupting chemicals (EDCs) are exogenous chemicals that have been found to disrupt ... -
Association of force plate and body-mounted inertial sensor measures for determination of hind limb lameness in horses
(University of Missouri--Columbia, 2015)The purpose of this study was to investigate the association between inertial sensor and stationary force plate measures of hind limb lameness. 21 adult horses that were either sound or had mild hind limb lameness were ... -
Examining the role of Gbx1 in spinal cord development and its contribution to mammalian locomotion
(University of Missouri--Columbia, 2015)Animals explore their environment through locomotion. Motion is largely generated by the activity of neurons in the spinal cord. Genes expressed during embryonic development are essential for the formation of connections ... -
Localization mechanisms of small plant-dwelling insects
(University of Missouri--Columbia, 2015)Movement is the basis of animal ecology, and understanding the causes and consequences of animal movement is a major goal of ecological research. Movement decisions involve an integrated process of sensory input and ... -
Molecular dissection of meiotic silencing by unpaired DNA
(University of Missouri--Columbia, 2015)Meiotic silencing by unpaired DNA (MSUD) is a genome surveillance mechanism that uses RNAi to protect against genetic parasites such as retrotransposons and viruses. This is accomplished by scanning the genome for DNA ... -
Molecular dissection of a genome defense pathway in Neurospora crassa
(University of Missouri--Columbia, 2015)Meiotic silencing by unpaired DNA (MSUD) is an RNA interference (RNAi) pathway in Neurospora crassa that detects genes without a homologous partner and silences them for the duration of sexual development. In this study, ... -
Does history repeat itself? : Impact of climate on floral resources for bumble bees then and now
(University of Missouri--Columbia, 2014) -
Integration of methods to study mate choice behavior in treefrogs
(University of Missouri--Columbia, 2014)My research incorporates results from a variety of methods to understand behavior. In my dissertation, I examined female behavior to novel, complex calls. In the gray treefrog species complex, Hyla versicolor and H. ... -
Spatial ecology of Western Ratsnakes (Pantherophis obsoletus) : implications for bird nest predation
(University of Missouri--Columbia, 2014)In fragmented Midwestern forests, many birds face high rates of nest predation, to the point where this region may serve as a population sink for some species. That is, so many of their eggs and young are eaten by predators ... -
Drivers of tree community composition and seed demography in Serengeti National Park - Tanzania
(University of Missouri--Columbia, 2015)Savannas are spatially diverse, variable and susceptible to high rates of disturbance from fire and herbivory. There is a significant amount of interest in woody species dynamics in relation to disturbance regimes but less ... -
Phylogeography and Population Genomics of the American Black Bear (Ursus americanus)
(University of Missouri--Columbia, 2015)The American black bear (Ursus americanus) is one of the eight living species of Ursidae, and the only one to have speciated in North America (1.8 - 1.2 Mya). This dissertation investigates the contemporary population ... -
It's a jungle out there : myoblasts, matrix, and MMPs.
(University of Missouri--Columbia, 2015)Extracellular Matrix: Mammalian skeletal muscle is notable for both its highly ordered biophysical structure and its regenerative capacity following trauma. Critical to both of these features is the specialized muscle ... -
Genetic and neuronal systems that are critical for high temperature avoidance in reflexive and learned behaviors
(University of Missouri--Columbia, 2014) -
Determining the mechanism of NF C-terminal mediated radial growth of myelinated axons
([University of Missouri--Columbia], 2014) -
Eph/Ephrin signalling in skeletal muscle development and regeneration
(University of Missouri--Columbia, 2014) -
Intrinsic, extrinsic and environmental regulation of muscle satellite cell motility
(University of Missouri--Columbia, 2011)Skeletal muscle repair and regeneration requires the activity of satellite cells, a population of myogenic stem cells. Previously, little data existed on the motility of satellite cells a critical component to tissue repair. ... -
Coordinated communication: an analysis of signal and preference phenotypes in the genus Hyla
(University of Missouri--Columbia, 2014)