RSS 1.0Division of Biological Sciences (MU)
The Division of Biological Sciences at MU offers a unique integration of world-class research, award-winning graduate and undergraduate training, and outstanding community outreach. Our faculty research programs include the acquisition of new knowledge through basic research, and coordinated translational research to improve human health, our food supply, and our environment. Our graduate training programs emphasize the excitement of discovery and the development of individual creativity and critical reasoning skills, with graduate mentors who are experts at the frontiers of their field. In undergraduate education, as in our graduate programs, we emphasize the excitement of discovery and the development of individual creativity and critical reasoning skills, providing an excellent foundation for advanced study or direct entry into the workplace. Because science exposure in the pre-college years is critical to the development of both scientists and informed citizens, we also offer special outreach programs for secondary school science teachers and their students in Missouri.
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Assessing the effects of anticoagulant rodenticides on non-target fish species
(University of Missouri--Columbia, 2018)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Invasive rat species have negatively affected island ecosystems contributing to the decline and extinction of many endemic species. The eradication of ... -
Developing tools for making inferences from genomic data
(University of Missouri--Columbia, 2019)The central question that the King lab seeks to answer is, "What happens on the genomic level when phenotypes evolve?" To this end, the core focus of my work has been on developing software and analytical methods that ... -
Metabolic responses of meniscal tissue to collagenase stimulation
(University of Missouri--Columbia, 2019)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Meniscal degeneration as a result of injury or aging is a common contributing factor in the development of knee OA. Meniscal degeneration develops and ... -
Regional mapping of the osteoarthritic joint
(University of Missouri--Columbia, 2019)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Osteoarthritis (OA) progresses from a focal lesion of articular cartilage to whole-joint inflammation and degradation. The "focal spread" progresses ... -
Establishing a foundation for large DNA transfer to artificial minichromosomes and B insert platforms in maize
(University of Missouri--Columbia, 2019)In plants, conventional genetic engineering methods limit the number of available traits that could potentially improve the quality of agriculture. Agrobacterium-mediated transformation and biolistic bombardment are tools ... -
The molecular underpinnings of neuronal cell identity in the stomatogastric ganglion of cancer borealis
(University of Missouri--Columbia, 2019)Throughout the life of an organism, the nervous system must be able to balance changing in response to environmental stimuli with the need to produce reliable, repeatable activity patterns to create stereotyped behaviors. ... -
Atypical localization of Eph-RTKs in childhood cancer rhabdomyosarcoma
(University of Missouri--Columbia, 2019)Rhabdomyosarcoma (RMS), the most common soft tissue tumor in children, is an aggressive cancer with a 5-year survival rate of 24% if it has metastasized. Current treatment options are limited to surgery, chemotherapy and ... -
Assessment of the microbiome associated with endangered orchids
(University of Missouri--Columbia, 2018)The Orchidaceae (orchid family) is perhaps the most speciose group of flowering plants with approximately 25,000 described species and many thousands of hybrids. While certain mycorrhizal fungi are required for orchids to ... -
Mechanisms of the phototropic pathway
(University of Missouri--Columbia, 2018)Plants are sessile organisms and therefore are limited in their ability to gather resources. Therefore, they have evolved several mechanisms that aid them in their quest to gather light, water and nutrients. One such ... -
PopZ and FtsZ coordinate polar growth termination and cell division in Agrobacterium tumefaciens
(University of Missouri--Columbia, 2018)Understanding how bacterial cells expand their cell walls is an important question with relevance to development of antibiotics. While many studies have focused on the regulation of bacterial elongation utilizing lateral ... -
The evolution of complex calls In meadow Katydids
(University of Missouri--Columbia, 2018)Meadow Katydids (genera Orchelimum and Conocephalus) are a specious group often are found in habitats with several species within the group living in sympatry. They produce complex calls with two distinct phrases, "buzzing" ... -
Genetic diversity and distribution of the ringed salamander (ambystoma annulatum) across multiple spatial scales
(University of Missouri--Columbia, 2018)Species distributions are governed by a complex suite of abiotic and biotic interactions that govern movement of individuals and are variable through time and space. These dynamic processes, such as shifts in temperature ... -
Periconceptional, gestational, and lactational exposure to unconventional oil and gas chemical mixture alters energy expenditure in adult female mice
(University of Missouri--Columbia, 2018)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Unconventional oil and gas (UOG) processes involves injection of pressurized water, chemicals, and suspended solids thousands of feet under the surface ... -
Mechanisms of photoreceptor mediated responses in photomorphogenesis and phototropism
(University of Missouri--Columbia, 2018)Photoreceptor facilitated light perception provides plants with critical environmental information from which they can direct their growth. We investigated the early photomorphogenic responses in Glycine max and Glycine ... -
The ecological roles of amphibians and subsidies in ponds
(University of Missouri--Columbia, 2018)Freshwater ponds are often underappreciated landscape features, despite the fact they comprise a major portion of all freshwater ecosystems. Ponds support diverse food webs and species not found in other habitat types. ... -
Plasticity of neurons in mouse major pelvic ganglia in response to loos of physiological input in cases of nerve injury and spinal cord injury
(University of Missouri--Columbia, 2018)Autonomic dysfunctions present significant effects on day to day functions of spinal cord-injured patients. Most people with spinal cord injury (SCI) reported a desire to recover autonomic functions such as bladder and ... -
Roles for the adhension molecule Contactin2 in the development and function of neural circuits in zebrafish
(University of Missouri--Columbia, 2018)Neuronal migration and axon guidance are critical developmental processes that are essential for establishing functional neural circuits underlying complex cognitive and motor functions. Precise neuronal migration and axon ... -
Understanding the effects of maternal undernutrition in early gestation on placental development in late gestation
(University of Missouri--Columbia, 2018)Chronic diseases such as cardiovascular disease and diabetes are on the rise among the U.S. population. Heart Disease is the leading cause of death in the US and is responsible 610,000 deaths per year. A suite of risk ... -
Stimulus specific adaptation in the hearing system of Neoconocephalus katydids (insecta: Orthoptera)
(University of Missouri--Columbia, 2017)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Stimulus Specific Adaptation (SSA) is a fundamental response that identifies novel signals within a repetitive background noise. It is well characterized ... -
Neuronal changes underlying altered biophysical properties of reticulospinal neurons following spinal cord injury in the lamprey
(University of Missouri--Columbia, 2017)Following a severe spinal cord injury (SCI), the descending axons of reticulospinal (RS) neurons are damaged, resulting in paralysis below the site of the injury. For higher vertebrates, including humans, RS neurons are ...