Browsing Biomedical and Health Informatics Electronic Theses (UMKC) by Thesis Advisor "Ye, Shui Qing, 1954-"
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Identification of novel coding single nucleotide polymorphisms associated with acute respiratory distress syndrome
(2014-07-28)ARDS is a lung condition characterized by impaired gas exchange with systemic release of inflammatory mediators, causing inflammation, hypoxemia and multiple organ failure. Disease susceptibility and progression are poorly ... -
Identification of Novel Regulatory Genes in Acetaminophen Induced Hepatocyte Toxicity by a Genome-Wide CRISPR/Cas9 Screen
(University of Missouri -- Kansas City, 2018)Acetaminophen (APAP) is a commonly used analgesic responsible for over 56,000 overdose-related emergency room visits annually. A long asymptomatic period and limited treatment options result in a high rate of liver ...