Biomedical Sciences Publications (UMKC)
Items in this collection are the scholarly output of the Department of Biomedical Sciences faculty, staff, and students, either alone or as co-authors, and which may or may not have been published in an alternate format.
Items in MOspace are protected by copyright, with all rights reserved, unless otherwise indicated.
Recent Submissions
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RNA-seq analysis of synovial fibroblasts brings new insights into rheumatoid arthritis
(2012-12-21)Abstract Background Rheumatoid arthritis (RA) is a chronic autoimmune-disease of unknown origin that primarily affects the joints and ultimately leads to their destruction. Growing evidence ... -
Associations between the built environment and physical activity in public housing residents
(2007-11-12)Abstract Background Environmental factors may influence the particularly low rates of physical activity in African American and low-income adults. This cross-sectional study investigated ... -
Gene selection for classification of microarray data based on the Bayes error
(2007-10-03)Abstract Background With DNA microarray data, selecting a compact subset of discriminative genes from thousands of genes is a ... -
HAPSIMU: a genetic simulation platform for population-based association studies
(2008-08-05)Abstract Background Population structure is an important cause leading to inconsistent results in population-based association ... -
The neuroprotective properties of palmitoylethanolamine against oxidative stress in a neuronal cell line
(2009-12-10)Abstract Background N-acylethanolamines (NAEs) are lipids upregulated in response to cell and tissue injury and are involved ... -
A new permutation strategy of pathway-based approach for genome-wide association study
(2009-12-18)Abstract Background Recently introduced pathway-based approach is promising and advantageous to improve the efficiency of ... -
Tocotrienols inhibit lipopolysaccharide-induced pro-inflammatory cytokines in macrophages of female mice.
(2010-12-16)Abstract Background Inflammation has been implicated in cardiovascular disease, and the important role of proteasomes in the development of inflammation and other macrophage functions has been demonstrated. ... -
delta-Tocotrienol and quercetin reduce serum levels of nitric oxide and lipid parameters in female chickens
(2011-02-28)Abstract Background Chronic, low-grade inflammation provides a link between normal ageing and the pathogenesis of age-related diseases. A series of in vitro tests confirmed the strong anti-inflammatory activities ... -
A Bayesian Analysis for Identifying DNA Copy Number Variations Using a Compound Poisson Process
(2010-08-17)To study chromosomal aberrations that may lead to cancer formation or genetic diseases, the array-based Comparative Genomic Hybridization (aCGH) technique is often used for detecting DNA copy number variants (CNVs). Various ... -
Tocotrienols-induced inhibition of platelet thrombus formation and platelet aggregation in stenosed canine coronary arteries.
(2011-04-14)Abstract Background Dietary supplementation with tocotrienols has been shown to decrease the risk of coronary artery disease. Tocotrienols are plant-derived forms of vitamin E, which have potent anti-inflammatory, ... -
Inhibition of nitric oxide and inflammatory cytokines in LPS-stimulated murine macrophages by resveratrol, a potent proteasome inhibitor
(2012-06-14)Abstract Background: Altered immune function during ageing results in increased production of nitric oxide (NO) and other inflammatory mediators. Recently, we have reported that NO production was inhibited ... -
Suppression of nitric oxide induction and pro-inflammatory cytokines by novel proteasome inhibitors in various experimental models
(2011-10-12)Abstract Background Inflammation has been implicated in a variety of diseases associated with ageing, including cancer, cardiovascular, and neurologic diseases. We have recently established that the proteasome ...