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    • University of Missouri-Columbia
    • Graduate School - MU Theses and Dissertations (MU)
    • Theses and Dissertations (MU)
    • Dissertations (MU)
    • 2011 Dissertations (MU)
    • 2011 MU dissertations - Freely available online
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    Mitochondrial complex I protein is related to residual feed intake in beef cattle

    Ramos, Marcelo Hentz
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    [PDF] Research.pdf (973.4Kb)
    [PDF] short.pdf (47.94Kb)
    Date
    2011
    Format
    Thesis
    Metadata
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    Abstract
    Residual feed intake (RFI) is a calculated using DMI as dependent variable and metabolic body weight (BW 0.75) and ADG as independent variable. Mitochondria complex I (mitochondrial NADH:ubiquinone oxidoreductase) is one of the least understood membrane bound protein complexes. Insulin resistance has been reported in calves, dairy cows, horses and swine. For all four mitochondria experiments, there was a significant difference (P < 0.05) between RFI and DMI but no difference (P > 0.05) was reported for ADG and MMBW. For experiments one, two and three, CI was greater (P < 0.05) for -RFI compared to other treatments. The correlation between CI and RFI was -0.37 (P = 0.02), -0.48 (P = 0.034), and -0.84 (P = 0.015) for experiment one, two and three, respectively. For experiment 4, animals with -RFI had a trend for greater concentration (P = 0.07) of Band I (protein S1) than +RFI. Correlation between RFI and Band I was -0.72 (P = 0.04). A regression was developed using Band I and RFI with RFI = 6.1715 -0.00015 Band I, R2 = 0.85, RMSE = 0.62. No significant difference (P > 0.05) was reported in any variable measured during both the glucose and epinephrine tolerance test. We concluded that mitochondrial function was at least in part responsible for differences among animals in metabolic efficiency. In addition, insulin resistance is not responsible for RFI classification in feedlot animals.
    URI
    https://doi.org/10.32469/10355/14444
    https://hdl.handle.net/10355/14444
    Degree
    Ph. D.
    Thesis Department
    Animal sciences (MU)
    Rights
    OpenAccess.
    This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.
    Collections
    • 2011 MU dissertations - Freely available online
    • Animal Sciences electronic theses and dissertations (MU)

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