dc.contributor.advisor | Kerley, Monty Stephen, 1960- | eng |
dc.contributor.author | Ramos, Marcelo Hentz | eng |
dc.date.issued | 2011 | eng |
dc.date.submitted | 2011 Fall | eng |
dc.description | Title from PDF of title page (University of Missouri--Columbia, viewed on May 30, 2012). | eng |
dc.description | The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file. | eng |
dc.description | Dissertation advisor: Dr. Monty Kerley | eng |
dc.description | Vita. | eng |
dc.description | Ph.D. University of Missouri-Columbia, 2011 | eng |
dc.description | "December 2011" | eng |
dc.description.abstract | Residual feed intake (RFI) is a calculated using DMI as dependent variable and metabolic body weight (BW 0.75) and ADG as independent variable. Mitochondria complex I (mitochondrial NADH:ubiquinone oxidoreductase) is one of the least understood membrane bound protein complexes. Insulin resistance has been reported in calves, dairy cows, horses and swine. For all four mitochondria experiments, there was a significant difference (P < 0.05) between RFI and DMI but no difference (P > 0.05) was reported for ADG and MMBW. For experiments one, two and three, CI was greater (P < 0.05) for -RFI compared to other treatments. The correlation between CI and RFI was -0.37 (P = 0.02), -0.48 (P = 0.034), and -0.84 (P = 0.015) for experiment one, two and three, respectively. For experiment 4, animals with -RFI had a trend for greater concentration (P = 0.07) of Band I (protein S1) than +RFI. Correlation between RFI and Band I was -0.72 (P = 0.04). A regression was developed using Band I and RFI with RFI = 6.1715 -0.00015 Band I, R2 = 0.85, RMSE = 0.62. No significant difference (P > 0.05) was reported in any variable measured during both the glucose and epinephrine tolerance test. We concluded that mitochondrial function was at least in part responsible for differences among animals in metabolic efficiency. In addition, insulin resistance is not responsible for RFI classification in feedlot animals. | eng |
dc.description.bibref | Includes bibliographical references. | eng |
dc.format.extent | vi, 67 pages | eng |
dc.identifier.oclc | 872561096 | eng |
dc.identifier.uri | https://doi.org/10.32469/10355/14444 | eng |
dc.identifier.uri | https://hdl.handle.net/10355/14444 | |
dc.language | English | eng |
dc.publisher | University of Missouri--Columbia | eng |
dc.relation.ispartofcommunity | University of Missouri--Columbia. Graduate School. Theses and Dissertations | eng |
dc.rights | OpenAccess. | eng |
dc.rights.license | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License. | |
dc.subject | feed intake | eng |
dc.subject | beef cattle | eng |
dc.subject | insulin resistance | eng |
dc.subject | mitochondrial function | eng |
dc.subject | metabolic efficiency | eng |
dc.title | Mitochondrial complex I protein is related to residual feed intake in beef cattle | eng |
dc.type | Thesis | eng |
thesis.degree.discipline | Animal sciences (MU) | eng |
thesis.degree.grantor | University of Missouri--Columbia | eng |
thesis.degree.level | Doctoral | eng |
thesis.degree.name | Ph. D. | eng |