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dc.contributor.advisorKerley, Monty Stephen, 1960-eng
dc.contributor.authorRamos, Marcelo Hentzeng
dc.date.issued2011eng
dc.date.submitted2011 Falleng
dc.descriptionTitle from PDF of title page (University of Missouri--Columbia, viewed on May 30, 2012).eng
dc.descriptionThe entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file.eng
dc.descriptionDissertation advisor: Dr. Monty Kerleyeng
dc.descriptionVita.eng
dc.descriptionPh.D. University of Missouri-Columbia, 2011eng
dc.description"December 2011"eng
dc.description.abstractResidual feed intake (RFI) is a calculated using DMI as dependent variable and metabolic body weight (BW 0.75) and ADG as independent variable. Mitochondria complex I (mitochondrial NADH:ubiquinone oxidoreductase) is one of the least understood membrane bound protein complexes. Insulin resistance has been reported in calves, dairy cows, horses and swine. For all four mitochondria experiments, there was a significant difference (P < 0.05) between RFI and DMI but no difference (P > 0.05) was reported for ADG and MMBW. For experiments one, two and three, CI was greater (P < 0.05) for -RFI compared to other treatments. The correlation between CI and RFI was -0.37 (P = 0.02), -0.48 (P = 0.034), and -0.84 (P = 0.015) for experiment one, two and three, respectively. For experiment 4, animals with -RFI had a trend for greater concentration (P = 0.07) of Band I (protein S1) than +RFI. Correlation between RFI and Band I was -0.72 (P = 0.04). A regression was developed using Band I and RFI with RFI = 6.1715 -0.00015 Band I, R2 = 0.85, RMSE = 0.62. No significant difference (P > 0.05) was reported in any variable measured during both the glucose and epinephrine tolerance test. We concluded that mitochondrial function was at least in part responsible for differences among animals in metabolic efficiency. In addition, insulin resistance is not responsible for RFI classification in feedlot animals.eng
dc.description.bibrefIncludes bibliographical references.eng
dc.format.extentvi, 67 pageseng
dc.identifier.oclc872561096eng
dc.identifier.urihttps://doi.org/10.32469/10355/14444eng
dc.identifier.urihttps://hdl.handle.net/10355/14444
dc.languageEnglisheng
dc.publisherUniversity of Missouri--Columbiaeng
dc.relation.ispartofcommunityUniversity of Missouri--Columbia. Graduate School. Theses and Dissertationseng
dc.rightsOpenAccess.eng
dc.rights.licenseThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.
dc.subjectfeed intakeeng
dc.subjectbeef cattleeng
dc.subjectinsulin resistanceeng
dc.subjectmitochondrial functioneng
dc.subjectmetabolic efficiencyeng
dc.titleMitochondrial complex I protein is related to residual feed intake in beef cattleeng
dc.typeThesiseng
thesis.degree.disciplineAnimal sciences (MU)eng
thesis.degree.grantorUniversity of Missouri--Columbiaeng
thesis.degree.levelDoctoraleng
thesis.degree.namePh. D.eng


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