Does supplementation with alpha-lipoic acid (ALA) lead to improved glycemic control in patients with type 2 diabetes?
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Small studies show ALA may reduce oxidative stress and improve insulin sensitivity in persons with diabetes. However, data are currently insufficient to support supplementation with ALA for improved glycemic control in patients with type 2 diabetes. (SOR: C, based on small RCTs and case-control studies without patient-oriented outcomes.)
Evidence Based Practice 15(5): 04.