How should we treat URIs in children?
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Nothing dramatically improves viral upper respiratory tract infection (URI) symptoms in children, but honey and vapor rubs appear to produce some benefits. Honey modestly improves cough and child sleep, but may be associated with hyperactivity (SOR: B, based on 1 blinded and 1 nonblinded RCT.) Vapor rubs modestly improve cough, congestion, and child sleep, but may be associated with local irritation. (SOR: B, based on 1 partially double-blind RCT.) Adjunctive nasal saline results in statistically but not clinically significant lower symptom scores. (SOR: B, based on 1 nonblinded RCT.) Neither zinc gluconate nor zinc sulfate decrease symptom severity or duration. (SOR: B, based on 2 double-blind RCTs.) Echinacea does not provide significant improvement in common cold symptoms in children. (SOR: B, based on 1 double-blind RCT.)
Evidence Based Practice 15(7): 01-02.