What is the best pharmaceutical treatment for adults with exercise-induced asthma?
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Inhaled short-acting beta2-agonists (SABAs) taken 10 to 15 minutes before exercise prevent exercise-induced bronchospasm in more than 80% of patients. (SOR: A, based on a systematic review.) In patients with frequent and severe exercise-induces asthma (EIA), daily use of an inhaled corticosteroid significantly reduces the frequency and severity of bronchoconstriction and improves spirometry results. (SOR: C, based on a systematic review with disease-oriented outcomes.) Long acting beta2-agonists (LABAs), leukotriene receptor antagonists, and mast-cell stabilizing agents (MCSAs) are also beneficial but are not recommended as first-line therapy. (SOR: C, based on evidence-based guidelines.)
Evidence Based Practice 15(7): 14.