Does weaning of narcotics in pregnant women with chronic pain result in better fetal outcomes than maintenance therapy?
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Only a paucity of direct data are available to inform us on this issue. Opioid treatment for chronic pain during pregnancy is associated with birth defects, neonatal abstinence syndrome, and other morbidities; however, the fetal risks of weaning off opioids during pregnancy are unknown. Opioid therapy for chronic pain during pregnancy should be used only if clear benefits outweigh these risks. (SOR: C, based on observational studies and expert opinion.)
Evidence Based Practice 15(7): 09-10.