How safe and effective are tear duct plugs for treating adults with dry eyes?
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Silicon plugs alone or after temporary collagen plugs are effective for alleviating moderate to severe dry-eye symptoms in adults in whom topical or systemic medical treatments have failed. Reported adverse effects include tear overflow, inflammation, and spontaneous plug loss. (SOR: B, based on 2 small RCTs and an evidence-based guideline of descriptive studies.)
Evidence Based Practice 15(8): 10-11.