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dc.contributor.authorGrover, Michael
dc.contributor.authorRutkowski, Richard
dc.contributor.authorNashelsky, Joan
dc.contributor.otherUniversity of Missouri-Columbia. School of Medicine. Department of Family and Community Medicine. Family Physicians Inquiries Network.en_US
dc.date.issued2012-10eng
dc.description.abstractThe evaluation of patients with elevated transaminase levels should be individualized based on the presence of symptoms or physical examination findings that suggest serious disease or hepatic decompensation. (Strength of Recommendation [SOR]: C, expert opinion.) The initial evaluation should determine specific etiologies, such as exposure to alcohol or hepatotoxic medications, viral hepatitis, or hemochromatosis. In patients with reassuring initial test results, lifestyle modification can reverse presumed nonalcoholic fatty liver disease (NAFLD), the most common cause of persistently elevated liver transaminase levels. (SOR: B, based on cohort trials.) Transaminase levels that are elevated for longer than six months warrant additional investigation, which may include ultrasonography, additional serology, and possible liver biopsy. (SOR: C, expert opinion.)en_US
dc.identifier.citationAmerican Family Physician, 86(8) 2012.en_US
dc.identifier.urihttp://hdl.handle.net/10355/15739
dc.publisherFamily Physicians Inquiries Networken_US
dc.subjectliver diseaseen_US
dc.subjectliver enzymesen_US
dc.subjectlifestyle modificationsen_US
dc.subject.lcshLiver -- Diseases -- Diagnosis
dc.subject.lcshAminotransferases
dc.titleEvaluation of elevated serum transaminase levelsen_US
dc.typeArticleen_US


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