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dc.contributor.authorManandhar, Nilaeng
dc.contributor.authorHuang, Xieng
dc.contributor.authorJan, Lily Yeheng
dc.contributor.meetingnameHealth Sciences Research Day (2012 : University of Missouri)eng
dc.date.issued2012eng
dc.description.abstractMedulloblastomas (MB), the most common pediatric central nervous system (CNS) tumor, is a neuroepithelial tumor characterized by its rapid progression, aggressive nature, and tendency to metastasize along the brain-spinal cord axis. Little is known about the functional effectors driving deregulated MB cell migration and metastasis. Studies with mouse MB tumor models have revealed that the expression of EAG2, a voltage-gated potassium channel, is markedly upregulated during MB tumorigenesis. Abundant expression of the EAG2 gene has also been detected in MB human specimens. In the present work, we have studied the functional role of EAG2 using two established human MB cell lines, DAOY and VMB11.eng
dc.format.extent1 postereng
dc.identifier.urihttp://hdl.handle.net/10355/16031
dc.languageEnglisheng
dc.relation.ispartofcommunityUniversity of Missouri--Columbia. Health Sciences Research Dayeng
dc.rightsOpenAccess.eng
dc.rights.licenseThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.eng
dc.subjectbrain tumoreng
dc.subjectcell migrationeng
dc.subjectvoltage-gated potassium channeleng
dc.subject.lcshPotassium channelseng
dc.subject.lcshMedulloblastomaeng
dc.titleFunctional study of a voltage-gated potassium channel during medulloblastoma cell migrationeng
dc.typePostereng


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