Is the use of PPIs associated with hypomagnesemia?
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Chronic use of proton pump inhibitors (PPIs) is associated with hypomagnesemia that is often refractory to oral or parenteral magnesium replacement. Healthcare professionals should consider checking baseline and periodic serum magnesium levels in patients expected to be on long-term PPI treatment or with other risk factors for hypomagnesemia (SOR: C, case series).
Evidence Based Practice 15(11): 10-11.