How effective is desmopressin for primary nocturnal enuresis?
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Desmopressin reduces the number of wet nights on average by one night per week. Approximately 20% to 30% of children achieve complete dryness during the treatment. However, the chance of relapse is high once treatment is discontinued (SOR: A, systematic review of RCTs).
Evidence Based Practice 15(12): 16-17.