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dc.contributor.authorKruse, Darcyeng
dc.contributor.corporatenameUniversity of Missouri-Columbia. Office of Undergraduate Researcheng
dc.contributor.meetingnameSummer Undergraduate Research and Creative Achievements Forum (2004 : University of Missouri--Columbia)eng
dc.date2004eng
dc.date.issued2004eng
dc.descriptionAbstract only availableeng
dc.description.abstractThe study of programmed cell death or aptosis in tumors has attracted increased interests. Recent research has shown that whether a cell lives or dies is related to its three dimensional environment such as the organization of cells and the surrounding extracellular matrix. Therefore, it is important to detect apoptotic cells and monitor their response to drug treatment in three dimensional tissues. In this project, a non-invasive biomedical imaging method was developed to achieve a holographic image of apoptotic cells in tumors. A setup based on a Mach-Zhender inferometer was used, with a HeNe laser (to be replaced by a near-infrared laser) as the light source. An electro-optic modulator was placed in the sample leg of the inferometer, producing frequencies on the order of 1 MHz which are unaffected by low frequency vibrations. The tissue can be scanned point by point and reconstructed in real time to create a clear three dimensional image on a visual display. This is an experiment still in process. Further understanding of tumor cells and finding a technology with which to effectively image the effect of drugs on these cells will help progress toward understanding and defeating cancer.eng
dc.description.sponsorshipLife Sciences Undergraduate Research Opportunity Programeng
dc.identifier.urihttp://hdl.handle.net/10355/1738eng
dc.languageEnglisheng
dc.publisherUniversity of Missouri--Columbia. Office of Undergraduate Researcheng
dc.relation.ispartof2004 Summer Undergraduate Research and Creative Achievements Forum (MU)eng
dc.relation.ispartofcommunityUniversity of Missouri-Columbia. Office of Undergraduate Research. Undergraduate Research and Creative Achievements Forumeng
dc.source.urihttp://undergradresearch.missouri.edu/forums-conferences/abstracts/abstract-detail.php?abstractid=eng
dc.subjectaptosis in tumorseng
dc.subjectapoptotic cellseng
dc.subjectcancer researcheng
dc.subjectthree dimensional imagingeng
dc.titleOptical imagining technique for viewing apoptotic cellseng
dc.typePresentationeng


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