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    • Office of Undergraduate Research (MU)
    • Undergraduate Research and Creative Achievements Forum (MU)
    • 2008 Undergraduate Research and Creative Achievements Forum (MU)
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    Analysis of genetic drift within the highly repetitive KSP repeat domain and neurofilament medium [abstract]

    Golik, Benjamin
    Barry, Devin
    Yager, Craig
    Garcia, Michael L.
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    [PDF] AnalysisGeneticDriftKSP.pdf (25.57Kb)
    Date
    2008
    Contributor
    University of Missouri-Columbia. Office of Undergraduate Research
    Format
    Presentation
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    Abstract
    Axonal diameter is one key component utilized to determine conduction velocity. However, the mechanism that influences axonal diameter must be stable within a given species, but flexible enough to adjust to the evolution of larger species. Altering the number of Phosphorylation sites within the C-terminus of NF-M is one potential mechanism that can satisfy both criteria. We have evidence for expanding the number of sites in larger species. I will determine if the number of sites remains stable within a species. Taken together, these results will support the role of NF-M Phosphorylation in influencing axonal diameter.
    URI
    http://hdl.handle.net/10355/1897
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    2008 Undergraduate Research and Creative Achievements Forum (MU)
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