Browsing Division of Food Systems and Bioengineering (MU) by Thesis Advisor "Gu, Li-Qun"
Now showing items 1-7 of 7
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Aptamer encoded nanopores as single molecule sensors
(University of Missouri--Columbia, 2008)We have created a low noise, calibrated, molecular-scaled pore. The nanopore is formed either by micro-forge polishing or external penetration of the nanocavity sealed in the pipette terminal. The nanopore fabrication is ... -
Characterization [of] nucleic acids unwinding and exploring its application in miRNA detection in the nanopore
(University of Missouri--Columbia, 2012)MicroRNAs (miRNAs) are a class of short (~14-27 nucleotides) noncoding RNAs that regulate gene expression at the post-transcriptional level. Aberrant expression of miRNAs has been found in all types of tumors. Reverse ... -
Detection of food contaminants by SERS and nanopore technology
(University of Missouri--Columbia, 2016)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] With growing consumption of aquaculture products, there is increasing demand on rapid and sensitive techniques that can detect prohibited substances ... -
Functional study of Kcv potassium channel through manipultion [sic] of individual subunits
(University of Missouri--Columbia, 2010)Potassium channels make up a ubiquitous, physiologically essential class of integral membrane proteins. Many K+ channels contain four identical symmetrically associated subunits. To explore the role of an individual subunit ... -
Single nucleotide polymorphism (SNP) discriminations by nanopore sensing
(University of Missouri--Columbia, 2018)Single Nucleotide Polymorphisms (SNPs) are a common type of nucleotide alterations across the genome. A rapid but accurate detection of individual or SNP panels can lead to the right and in-time treatments which possibly ... -
Single-molecule investigation and nanopore-integrated biochip
(University of Missouri--Columbia, 2008)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Chlorella-encoded membrane protein Kcv was synthesized and purified in vitro. By co-synthesis and assembly of wild type with tagged version of Kcv, ... -
Study of dielectrophoresis effect of dipolar molecules in electric field of nanopore and development of medical diagnostic nanopore sensor
(University of Missouri--Columbia, 2015)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The nanopore sensor can detect cancer-derived nucleic acid biomarkers such as microRNAs (miRNAs), providing a noninvasive tool potentially useful in ...