Browsing College of Veterinary Medicine (MU) by Thesis Semester "2013 Fall"
Now showing items 1-5 of 5
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Defining the therapeutic window in spinal muscular atrophy :
(University of Missouri--Columbia, 2013)Spinal muscular atrophy (SMA) is caused by the loss of a single gene, survival motor neuron-1 (SMN1), which results in the rapid deterioration of motor neuron integrity and function, most often leading to infantile death. ... -
Development of model systems for the vector-host-pathogen interface of bubonic plague
(University of Missouri--Columbia, 2013)Bubonic plague infections begin in the dermis when the pathogen is introduced by a flea during a routine blood feed. Several barriers separate Yersinia pestis from its replicative niche, including phagocytic cells in the ... -
Neurons projecting to the paraventricular nucleus of the hypothalamus are activated and contribute to cardiorespiratory responses to systemic acute hypoxia
(University of Missouri--Columbia, 2013)Activation of peripheral and central chemoreceptors contributes to homeostatic responses that maintain optimal blood gas levels, including oxygen and carbon dioxide. Brainstem neurons in the nTS and CVLM integrate and ... -
The use of a lysostaphin fusion protein as a dry-cow treatment for chronic Staphylococcus aureua mastitis in dairy cattle
(University of Missouri--Columbia, 2013)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] This study evaluated the efficacy of a lysostaphin-fusion protein (Lyso-PTD) as a dry-cow therapy for the treatment of experimentally-induced chronic, ... -
Vascular actions of insulin in cardiometabolic disease : effects of metformin, physical activity, and intrinsic aerobic fitness
(University of Missouri--Columbia, 2013)Insulin has important vascular and metabolic actions. The vascular effects of insulin typically account for as much as 40-50% of insulin-stimulated glucose disposal. However, the vascular reactivity to insulin is impaired ...