Browsing College of Veterinary Medicine (MU) by Thesis Advisor "Clarke, Lane L. (Lane Leroy)"
Now showing items 1-4 of 4
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The cystic fibrosis transmembrane conductance regulator and acid-base transporters of the murine duodenum
(University of Missouri--Columbia, 2006)The alkaline mucus barrier of the duodenum plays an important role in protecting the epithelium from acidic chyme entering from the stomach. Active HCO₃⁻ secretion involves the apical membrane activities of the cystic ... -
The effect of sodium/hydrogen exchanger inhibition on chemotherapy-induced intestinal epithelial damage
(University of Missouri--Columbia, 2017)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The small intestinal epithelium is one of the most rapidly dividing tissues in the mammalian body, making it an inadvertent target of non-specific ... -
Hyperproliferation and altered Wnt signaling in the cystic fibrosis mouse intestine /
(University of Missouri--Columbia, 2016)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis membrane conductance regulator (CFTR), a Cl- and HCO3 - channel expressed in several ... -
The role of CFTR in regulating the cell cycle of intestinal stem cells
(University of Missouri--Columbia, 2016)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] [Abstract taken from public pdf.] Cystic fibrosis (CF) patients and CF mouse models have an increased risk for gastrointestinal (GI) cancer. Intestinal ...