Now showing items 1-20 of 1483

  • Should RAAS blockade therapy be continued in patients with advanced renal disease? 

    Pham, Kim; Beyer, Carli; Guthmann, Rick (Family Physicians Inquiries Network, 2023-04)
    Q: Should RAAS blockade therapy be continued in patients with advanced renal disease? Evidence-based answer: PROBABLY. Renin-angiotensinaldosterone system (RAAS) blockade therapy should be continued in most patients with ...
  • Is there benefit to adding ezetimibe to a statin for the secondary prevention of CVD? 

    Reddy, Vinay; Allison, James; Mounsey, Anne; Guthmann, Rick (Family Physicians Inquiries Network, 2023-06)
    Q: Is there benefit to adding ezetimibe to a statin for the secondary prevention of CVD? Evidence-based answer: YES. In patients with known cardiovascular disease (CVD), ezetimibe with a statin decreases major adverse ...
  • Should antenatal testing be performed in patients with a pre-pregnancy BMI ≥ 35? 

    Dresang, Lee; Vellardita, Lia; Guthmann, Rick (Family Physicians Inquiries Network, 2023-03)
    Q: Should antenatal testing be performed in patients with a pre-pregnancy BMI ≥ 35? Evidence-based answer:Possibly. Elevated BMI is associated with an increased risk for stillbirth (strength of recommendation [SOR], B; ...
  • Is low-dose naltrexone effective in chronic pain management? 

    Radi, Roxanne; Huang, Harriet; Rivera, Jason; Lyon, Corey; DeSanto, Kristen; Guthmann, Rick (Family Physicians Inquiries Network, 2023-09)
    Q: Is low-dose naltrexone effective in chronic pain management? Evidence-based answer: YES. Low-dose naltrexone is as effective as amitriptyline in the treatment of painful diabetic neuropathy and has a superior safety ...
  • Does use of continuous or flash glucose monitors decrease hypoglycemia episodes in T2D? 

    Wen, Frances K.; Bigelow, Simone; Crosby, Kimberly; Reeder, Raye; Hoberecht, Toni; Moreau, Emrys; Guthmann, Rick (Family Physicians Inquiries Network, 2023-07)
    Q: Does use of continuous or flash glucose monitors decrease hypoglycemia episodes in T2D? Evidence-based answer: NO. In adults with insulin-treated type 2 diabetes (T2D), continuous glucose monitoring (CGM) and flash ...
  • Does regular walking improve lipid levels in adults? 

    Hatchell, Kayla; Chin, Emily; Vukelic, Brian; Fortenberry, Katherine; Ose, Dominick; Taylor, Eliza; Goossen, Rachel; Guthmann, Rick (Family Physicians Inquiries Network, 2023-01)
    Q: Evidence-based answer: Minimally. Regular moderateintensity walking for a period of 4 or more weeks minimally decreased total cholesterol (TC) and low-density lipoprotein (LDL) levels by about 7 mg/dL in women with ...
  • Does physical exercise reduce dementia-associated agitation? 

    Jabbour, Katarzyna; Wilson, Lynn M.; Mathieu, Susan S.; Keister, Drew; Guthmann, Rick (Family Physicians Inquiries Network, 2023-01)
    Q: Evidence-based answer: not consistently. Physical exercise demonstrates inconsistent benefit for neuropsychiatric symptoms, including agitation, in patients with dementia (strength of recommendation: b, inconsistent ...
  • Does hormone replacement therapy prevent cognitive decline in postmenopausal women? 

    Gates, Madeline; Beagle, Melissa; Bull, Lauren; Radi, Roxanne; Lyon, Corey; DeSanto, Kristen; Guthmann, Rick (Family Physicians Inquiries Network, 2023-05)
    Q: Evidence-based answer: NO. Hormone replacement therapy (HRT) does not prevent cognitive decline in postmenopausal women—and in fact, it may slightly increase risk (strength of recommendation, A; systematic review, ...
  • How does gender-affirming hormone therapy affect QOL in transgender patients? 

    Wilhelm, Sarah; Kelsberg, Gary; Safranek, Sarah; Guthmann, Rick (Family Physicians Inquiries Network, 2022-12)
    Q: How does gender-affirming hormone therapy affect QOL in transgender patients? Evidence-based answer: There are modest effects on depression but not anxiety. Gender-affirming hormone therapy (GAHT) is associated with ...
  • How accurate is transcutaneous bilirubin testing in newborns with darker skin tones? 

    Boden, Brandi; Buescher, Brittany; Kim, Amanda; Neher, Jon O.; Safranek, Sarah; Guthmann, Rick (Family Physicians Inquiries Network, 2022-11)
    Q: How accurate is transcutaneous bilirubin testing in newborns with darker skin tones? Evidence-based answer: Fairly accurate. Photometric transcutaneous bilirubin (TcB) testing may overestimate total serum bilirubin (TSB) ...
  • Which anticoagulant is safest for frail elderly patients with nonvalvular A-fib? 

    Earwood, J. Scott; Wilkie, Justin L.; Fernandez-Vasquez, Jennifer L. (Family Physicians Inquiries Network, 2022-11)
    Consider apixaban, which demonstrated a lower adverse event (AE) rate than warfarin regardless of frailty status, for anticoagulation treatment of older patients with nonvalvular atrial fibrillation (AF); by comparison, ...
  • What BP target is appropriate for pregnant patients with mild chronic hypertension? 

    Lombardo, Cynthia; Morris, Laura (Family Physicians Inquiries Network, 2023-01)
    Treat mild chronic hypertension during pregnancy to a target of [greater than] 140/90 mm Hg to reduce the risk for adverse pregnancy outcomes.
  • Put down the electronics after a concussion? 

    Rabaza, Cristina; Piggott, Cleveland (Family Physicians Inquiries Network, 2023-01)
    Advise your teenaged and young adult patients with concussion to avoid electronic screens in the first 48 hours after a concussion to minimize time to symptom resolution.
  • Is self-administered DMPA an answer to contraception access in the post-Roe era? 

    Nakaishi, Lindsay; Castelli, Gregory (Family Physicians Inquiries Network, 2023-03)
    Consider prescribing self-administered subcutaneous depot medroxyprogesterone acetate (DMPA) for contraception instead of provider-administered DMPA. Self-administration improves contraception continuation rates without ...
  • Is combination pharmacotherapy effective for patients with acute depression? 

    Cardon, Brock; Schirding, Stephanie (Family Physicians Inquiries Network, 2023-04)
    Use a combination of a presynaptic α2-autoreceptor antagonist (eg, mirtazapine or trazodone) and a monoamine reuptake inhibitor (eg, selective serotonin reuptake inhibitor [SSRI], serotonin-norepinephrine reuptake inhibitor ...
  • Consider this tool to reduce antibiotic-associated adverse events in patients with sepsis 

    Mott, Timothy; Orme, Zachary (Family Physicians Inquiries Network, 2023-01)
    For patients hospitalized with sepsis, consider procalcitonin (PCT)-guided early discontinuation of antibiotic therapy for fewer infection-associated adverse events (AEs).
  • Consider this SGLT2 inhibitor for patients with HF with preserved ejection fraction 

    Produttur, Sanketh; Castelli, Gregory (Family Physicians Inquiries Network, 2022-12)
    Consider adding empagliflozin 10 mg to usual therapy to reduce hospitalization of symptomatic patients with heart failure with preserved ejection fraction (HFpEF; EF > 40%) and an N-terminal pro–B-type natriuretic peptide ...
  • Does an early COPD diagnosis improve long-term outcomes? 

    Bernet, Dan; Randolph, Charles; Neher, Jon O.; Safranek, Sarah (Family Physicians Inquiries Network, 2022-10)
    Q Does an early COPD diagnosis improve long-term outcomes? Evidence-based answer: It depends. A diagnosis of chronic obstructive pulmonary disease (COPD) made using screening spirometry in patients without symptoms does ...
  • Noncardiac inpatient has acute hypertension: Treat or not? 

    Marshall, Robert C.; Thiel, Derrick J.; Samar, Haroon (Family Physicians Inquiries Network, 2022-09)
    A retrospective study found more harm than benefit from treating elevated blood pressure in hospitalized noncardiac patients.
  • A "no-biopsy" approach to diagnosing celiac disease 

    Mott, Timothy; Gray, Carrie; Storey, Jon (Family Physicians Inquiries Network, 2022-10)
    This noninvasive alternative to the diagnostic gold standard may cut risk and expense for adult patients.