Clinical Inquiries

Description: Clinical Inquiries provide the ideal answers to clinical questions: using a structured search, critical appraisal, authoritative recommendations, clinical perspective, and rigorous peer review, Clinical Inquiries deliver best evidence for point of care use.
Publisher: Family Physicians Inquiries Network
Frequency: Irregular

Collections in this community

Recent Submissions

  • What’s the best test for underlying osteomyelitis in patients with diabetic foot ulcers? 

    Khodaee, Morteza; Lombardo, Daniel; Montgomery, Linda C.; Lyon, Corey; Montoya, Cathy (Family Physicians Inquiries Network, 2015-05)
    A: What’s the best test for underlying osteomyelitis in patients with diabetic foot ulcers? A: Magnetic resonance imaging (MRI) has a higher sensitivity and specificity (90% and 79%) than plain radiography (54% and 68%) ...
  • Do statins increase the risk of developing diabetes? 

    Parker, Kristin; Dohr, Karen; Neher, Jon O.; Kelsberg, Gary; St. Anna, Leilani (Family Physicians Inquiries Network, 2015-04)
    Q: Do statins increase the risk of developing diabetes? A: Yes. Statin therapy produces a small increase in the incidence of diabetes: one additional case per 255 patients taking statins over 4 years (strength of recommendation ...
  • What therapies alleviate symptoms of polycystic ovary syndrome? 

    Moreno, Laura; Bonnell, Ashley; Neher, Jon O.; Safranek, Sarah (Family Physicians Inquiries Network, 2015-04)
    Q: What therapies alleviate symptoms of polycystic ovary syndrome? A: Treatment of polycystic ovary syndrome (PCOS) in women not actively seeking to become pregnant is symptom-specific. Lifestyle modification (LSM) reduces ...
  • Does primary nocturnal enuresis affect childrens’ self-esteem? 

    Phung, Phuc; Kelsberg, Gary (Family Physicians Inquiries Network, 2015-04)
    Q: Does primary nocturnal enuresis affect childrens’ self-esteem? A: Yes. Children with primary nocturnal enuresis often, but not always, score about 10% lower on standardized rating scales for self esteem, or scores for ...
  • Are inhaled steroids effective for a postviral cough? 

    Insel, Kimberly; Lyon, Corey (Family Physicians Inquiries Network, 2015-03)
    Q: Are inhaled steroids effective for a postviral cough? Evidence-based answer: No. Inhaled corticosteroids (ICS) don’t improve postviral cough in adults with subacute (3-8 weeks) or chronic (>8 weeks) cough, adolescents ...
  • What is the best beta-blocker for systolic heart failure? 

    Hulknower, Stephen; Aiken, Benjamin A. (Family Physicians Inquiries Network, 2015-02)
    Q: What is the best beta-blocker for systolic heart failure? Evidence-based answer: Three beta-blockers—carvedilol, metoprolol succinate, and bisoprolol—reduce mortality equally (by about 30% over one year) in patients ...
  • Does topical diclofenac relieve osteoarthritis pain? 

    Hodge, Bryan; Skolnik, Debbie (Family Physicians Inquiries Network, 2015-02)
    Q: Does topical diclofenac relieve osteoarthritis pain? Evidence-based answer: Yes, at least in the short term. Topical diclofenac, with and without dimethyl sulfoxide (DMSO), modestly improves pain and function scores (by ...
  • Are inhaled steroids effective for a postviral cough? 

    Insel, Kimberly; Lyon, Corey (Family Physicians Inquiries Network, 2015-03)
    Q: Are inhaled steroids effective for a postviral cough? Evidence-based answer: No. Inhaled corticosteroids (ICS) don’t improve postviral cough in adults with subacute (3-8 weeks) or chronic (>8 weeks) cough, adolescents ...
  • How well do antivirals shorten genital herpes pain duration? 

    Yip, Stephen T.; Liu, Robyn; Warrington, Thomas; Webb, Charles W. (Family Physicians Inquiries Network, 2015-03)
    Q: How well do antivirals shorten genital herpes pain duration? Evidence-based answer: Oral and intravenous (IV) acyclovir each shorten the duration of pain for a first primary outbreak of herpes by about 50%; topical ...
  • Does the presence of a trained support person during labor decrease C-section rates? 

    Baum, Alison; Crawford, Paul; Humphrey-Shelton, Maureen (Family Physicians Inquiries Network, 2015-03)
    Q: Does the presence of a trained support person during labor decrease C-section rates? Evidence-based answer: sometimes. The continuous presence of a support person during labor slightly decreases (by about 2%) the ...
  • Is red-yeast rice a safe and effective alternative to statins? 

    Chen, Hsiang-Hwa; Safranek, Sarah (Family Physicians Inquiries Network, 2015-02)
    Q: Is red-yeast rice a safe and effective alternative to statins? Evidence-based answer: Yes, but perhaps not the redyeast rice extracts available in the United States. In patients with known coronary artery disease and ...
  • Does frenotomy help infants with tongue-tie overcome breastfeeding difficulties? 

    Cawse-Lucas, Jeanne; Waterman, Shannon; St. Anna, Leilani (Family Physicians Inquiries Network, 2015-02)
    Q: Does frenotomy help infants with tongue-tie overcome breastfeeding difficulties? Evidence-based answer: Probably not. No evidence exists for improved latching after frenotomy, and evidence concerning improvements in ...
  • Do annual pelvic exams benefit asymptomatic women who receive regular Pap smears? 

    Gold, Erin; Guthmann, Richard; Plonka, Catherine (Family Physicians Inquiries Network, 2015-01)
    Q: Do annual pelvic exams benefit asymptomatic women who receive regular Pap smears? Evidence-based answer: No evidence exists to support a clinical benefit from annual pelvic examinations for asymptomatic women who receive ...
  • Apolipoproteins for Cardiovascular Risk Assessment 

    Chang, Jennifer G.; Paulson, Christopher P.; Smith, Rita F. (Family Physicians Inquiries Network, 2014-04)
    Clinical Question: Is measurement of apolipoproteins better than traditional lipid measurements for predicting cardiovascular risk? Evidence-Based Answer: Measurement of apolipoprotein B and apolipoprotein A-I is no better ...
  • Which risk factors and signs and symptoms are associated with coccidioidomycosis? 

    Crawford, Paul; Peterson, Timothy; Honeycutt, J. David (Family Physicians Inquiries Network, 2014-12)
    Q: Which risk factors and signs and symptoms are associated with coccidioidomycosis? Evidence-Based Answer: Risk factors for coccidioidomycosis, or valley fever, include lower respiratory tract symptoms lasting longer than ...
  • Is immediate-release topiramate an effective treatment for adult obesity? 

    Harshman, Heather; Kovach, Fran (Family Physicians Inquiries Network, 2014-12)
    Q: Is immediate-release topiramate an effective treatment for adult obesity? Evidence-Based Answer: Yes. Topiramate (at daily doses of 64-400 mg) produces an average 5.34 kg of additional weight loss compared with placebo ...
  • Does any antidepressant besides bupropion help smokers quit? 

    Espanol, Eddie; Kelsberg, Gary; Safranek, Sarah (Family Physicians Inquiries Network, 2014-11)
    Q: Does any antidepressant besides bupropion help smokers quite? Evidence-based answer: Yes, nortriptyline approximately doubles smoking cessation rates, an effect comparable to bupropion. Adding nortriptyline to nicotine ...
  • What treatments relieve arthritis and fatigue associated with systemic lupus erythematosus? 

    Jones, Daniel W.; Wright, Derek; Jankowski, Terry Ann (Family Physicians Inquiries Network, 2014-10)
    Q: What treatments relieve arthritis and fatigue associated with systemic lupus erythematosus? A: Hydroxychloroquine and chloroquine improve the arthritis associated with mild systemic lupus erythematosus (SLE)—producing ...
  • Do oral contraceptives put women with a family history of breast cancer at increased risk? 

    Freund, Rachel; Kelsberg, Gary; Safranek, Sarah (Family Physicians Inquiries Network, 2014-09)
    Q. Do oral contraceptives put women with a family history of breast cancer at increased risk? Evidence-based answer: No. Modern combined oral contraceptive pills (OCPs) don’t increase breast cancer risk in women with a ...
  • What is the best nonsurgical therapy for pelvic organ prolapse? 

    Overby, Zachariah; Persons, Robert K.; Carrillo, Misty J. (Family Physicians Inquiries Network, 2014-08)
    Q. What is the best nonsurgical therapy for pelvic organ prolapse? Evidence-based answer: Pelvic floor muscle training (PFMT) and pessaries are equally effective in treating symptoms of pelvic organ prolapse (POP). PFMT ...

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