Clinical Inquiries (MU)
|Description:||Clinical Inquiries provide the ideal answers to clinical questions: using a structured search, critical appraisal, authoritative recommendations, clinical perspective, and rigorous peer review. Clinical Inquiries deliver best evidence for point of care use.|
|Publisher:||Family Physicians Inquiries Network|
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- Clinical Inquiries, 2001
- Clinical Inquiries, 2002
- Clinical Inquiries, 2003
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- Clinical Inquiries, 2012
- Clinical Inquiries, 2013
- Clinical Inquiries, 2014
- Clinical Inquiries, 2015
- Clinical Inquiries, 2016
- Clinical Inquiries, 2017
- Clinical Inquiries, 2018
- Clinical Inquiries, 2019
(2019)Q: How safe and effective is ondansetron for nausea and vomiting in pregnancy? Evidence-based answer: oral ondansetron is more effective than a combination of pyridoxine and doxylamine for outpatient treatment of nausea ...
(2019)Q Which oral nonopioid agents are most effective for OA pain? Evidence-based answer: nonsteroidal anti-inflammatory drugs (nsaids), when used at the maximum clinically effective dose, reduce osteoarthritis (OA) pain in ...
(2019)Q Do A-fib patients continue to benefit from vitamin K antagonists with advancing age? Evidence-based answer: yes, patients with atrial fibrillation who are between the ages of 50 and 90 years continue to benefit from ...
(2019)Q Can unintended pregnancies be reduced by dispensing a year’s worth of hormonal contraception? Evidence-based answer: probably, although studies that looked directly at this outcome are limited. A systematic review showed ...
(2019)Q: How effective is spironolactone for treating resistant hypertension? EVIDENCE-BASED ANSWER: VERY EFFECTIVE. Spironolactone reduces systolic blood pressure (SPB) by 11 to 17 mm Hg and diastolic blood pressure (DPB) by ...
(2019)Q: Does withholding an ACE inhibitor or ARB before surgery improve outcomes? EVIDENCE-BASED ANSWER: A GUARDED YES, because the evidence of benefit is from observational studies and applies to noncardiac surgery. Withholding ...
(2019)Q: What are the risks of long-term PPI for GERD symptoms in patients > 65 years? EVIDENCE-BASED ANSWER: THE USE OF PROTON PUMP INHIBITORS (PPIs) to control gastrointestinal esophageal reflux disease (GRED) is significantly ...
(2019-03)Q: Is intra-articular platelet-rich plasma injection an effective treatment for knee OA? EVIDENCE-BASED ANSWER: PROBABLY NOT, based on the balance of evidence. While low-quality evidence may suggest potential benefit, the ...
Does left atrial appendage closure reduce stroke rates as well as oral anticoagulants and antiplatelet meds in A-fib patients? (2019-01)Q: Does left atrial appendage closure reduce stroke rates as well as oral anticoagulants and antiplatelet meds in A-fib patients? EVIDENCE-BASED ANSWER: Yes. Left atrial appendage closure (LAAC) with the Watchman device ...
(2018-12)Q: Does amniotomy shorten spontaneous labor or improve outcomes? Evidence-based answer: No. Amniotomy neither shortens spontaneous labor nor improves any of the following outcomes: length of first stage of labor, cesarean ...
(2018-11)Q: What medical therapies work for gastroparesis? Evidence-based answer: It’s unclear if there are any highly effective medications for gastroparesis (TABLE1-10). Metoclopramide improves the sense of fullness by about 40% ...
(2018-10)Q: What’s the best VTE treatment for patients with cancer? Evidence-based answer: No. Head-to-head studies directly compare all the main treatments for venous thromboembolism (VTE) in cancer patients. Long-term treatment ...
(2018-10)Q: How effectively do ACE inhibitors and ARBs prevent migraines? Evidence-based answer: The angiotensin-converting enzyme (ACE) inhibitor lisinopril reduces the number of migraines by about 1.5 per month in patients ...
(2018-09)Q: Do statins alter the risk or progression of dementia? Evidence-based answer: No. Moderate-intensity statin therapy (with pravastatin or simvastatin) doesn’t prevent progression to dementia in patients at increased risk. ...
(2018-09)Q: How often does long-term PPI therapy cause clinically significant hypomagnesemia? EVIDENCE-BASED ANSWER: Rarely. Proton pump inhibitors (PPIs) may be associated with decreases in serum magnesium laboratory values to ...
(2018-08)Q: What’s the best secondary treatment for patients who fail initial triple therapy for H pylori? Evidence-based answer: treating patients with Helicobacter pylori infection who have failed clarithromycin-based triple ...
(2018-07)Q: Can CBT effectively treat adult insomnia disorder? Evidence-based answer: Yes. Cognitive behavioral therapy (CBT) administered individually, in a group setting, or on the internet is effective for treating insomnia in ...
(2018-07)Q: What are the benefits/risks of giving betamethasone to women at risk of late preterm labor? Evidence-based answer: Giving betamethasone to women at risk for delivery between 34 weeks 0 days and 36 weeks 6 days can lower ...
(2018-06)Q Does prophylactic azithromycin reduce the number of COPD exacerbations or hospitalizations? EVIDENCE-BASED ANSWER: Yes for exacerbations, no for hospitalizations. Prophylactic azithromycin reduces the number of exacerbations ...
(2018-06)Q: How effective and safe is fecal microbial transplant in preventing C difficile recurrence? Evidence-based answer: fecal microbial transplant (fmt) is reasonably safe and effective. In patients who have had multiple ...