Clinical Inquiries

Description: Clinical Inquiries provide the ideal answers to clinical questions: using a structured search, critical appraisal, authoritative recommendations, clinical perspective, and rigorous peer review. Clinical Inquiries deliver best evidence for point of care use.
Publisher: Family Physicians Inquiries Network
Frequency: Irregular

Collections in this community

Recent Submissions

  • Does knuckle popping lead to arthritis? 

    Powers, Tye; Kelsberg, Gary; Safranek, Sarah (2016-10)
    Q: Does knuckle popping lead to arthritis? Evidence-based answer: No, habitual knuckle popping, or cracking (over the course of several decades) isn’t associated with clinical or radiographic evidence of osteoarthritis ...
  • Which SSRIs most effectively treat depression in adolescents? 

    DeLucia, Valory; Kelsberg, Gary; Safranek, Sarah (2016-09)
    Q: Which SSRIs most effectively treat depression in adolescents? Evidence-based answer: We don’t know which selective serotonin reuptake inhibitors (SSRIs) are the most effective and safe because no studies have compared ...
  • Which treatments are safe and effective for chronic sinusitis? 

    Over, Darrell R. (2016-11)
    Q: Which treatments are safe and effective for chronic sinusitis? Evidence-based answer: for adults with chronic rhinosinusitis (crs), intranasal steroid (ins) therapy is more likely than placebo to improve symptoms (50% ...
  • Which patients with metabolic syndrome benefit from metformin? 

    Stover, Liz; Kelsberg, Gary; Safranek, Sarah (2016-11)
    Q Which patients with metabolic syndrome benefit from metformin? Evidence-based answer: patients at highest risk for progression to diabetes benefit from metformin. In patients with metabolic syndrome who are in the ...
  • How do clinical prediction rules compare with joint fluid analysis in diagnosing gout? 

    Westerfield, Katie L; Mounsey, Anne; Nashelsky, Joan (2016-11)
    Q: How do clinical prediction rules compare with joint fluid analysis in diagnosing gout? Evidence-based answer: clinical prediction rules effectively diagnose gout without joint fluid analysis. The American College of ...
  • Which nonhormonal treatments are effective for hot flashes? 

    Kelsberg, Gary; Maragh, Leticia; Safranek, Sarah (2016-05)
    Q Which nonhormonal treatments are effective for hot flashes? Evidence-based answer: Selective serotonin reuptake inhibitors (SSRIs [fluoxetine, sertraline, paroxetine]) and the selective norepinephrine reuptake inhibitor ...
  • Does caffeine intake during pregnancy affect birth weight? 

    Adams, Taralee; Kelsberg, Gary; Safranek, Sarah (Family Physicians Inquiries Network, 2016-03)
    Q: Does caffeine intake during pregnancy affect birth weight? Evidence-based answer: No. Reducing caffeinated coffee consumption by 180 mg of caffeine (the equivalent of 2 cups) per day after 16 weeks-gestation doesn't ...
  • Is lower BP worth it in higher-risk patients with diabetes or coronary disease? 

    Kelsberg, Gary; Russell, Telly; Safranek, Sarah (Family Physicians Inquiries Network, 2016-02)
    Q: Is lower BP worth it in higher-risk patients with diabetes or coronary disease? Evidence-based answer: There is no simple answer; the risk/benefit picture is complicated. Controlling blood pressure to a target of 130/80 ...
  • Do corticosteroid injections improve carpal tunnel syndrome symptoms? 

    Lyon, Corey; Syfert, Jonathan; Nashelsky, Joan (Family Physicians Inquiries Network, 2016-02)
    Q: Do corticosteroid injections improve carpal tunnel syndrome symptoms? Evidence-based answer: Yes. injected corticosteroids reduce symptoms of carpal tunnel syndrome (CTS) more effectively than placebo or systemic steroids, ...
  • What’s the best way to predict the success of a trial of labor after a previous C-section? 

    Warren, Johanna B.; Hamilton, Andrew (Family Physicians Inquiries Network, 2015-12)
    Q: What's the best way to predict the success of a trial of labor after a previous C-section? Evidence-based answer: while 8 scoring tools predict success rates for a trial of labor after previous cesarean section (TOLAC), ...
  • Is arthroscopic subacromial decompression effective for shoulder impingement? 

    Ashbaugh, Andrew; Neher, Jon O.; Safranek, Sarah (Family Physicians Inquiries Network, 2015-11)
    Q: Is arthroscopic subacromial decompression effective for shoulder impingement? Evidence-based answer: It's impossible to say for certain in the absence of randomized controlled trials. However, in patients whose impingement ...
  • Does high dietary soy intake affect a woman’s risk of primary or recurrent breast cancer? 

    Eakin, Angie; Kelsberg, Gary; Safranek, Sarah (Family Physicians Inquiries Network, 2015-10)
    Q. Does high dietary soy intake affect a woman's risk of primary or recurrent breast cancer? Evidence-based answer: No, it doesn't affect the risk of primary breast cancer, but it does (favorably) affect the risk of cancer ...
  • How effective are opioids for chronic low back pain? 

    Freund, Jeffrey; Kraus, Connie; Hopper-Lane, Christopher (Family Physicians Inquiries Network, 2015-09)
    Q: How effective are opioids for chronic low back pain? Evidence-based answer: Short-term (<4 months) treatment with opioids provides modest relief of chronic low back pain, but only minimal improvement in function compared ...
  • Does qHPV vaccine prevent anal intraepithelial neoplasia and condylomata in men? 

    shum, Johnny; Kelsberg, Gary; Safranek, Sarah (Family Physicians Inquiries Network, 2015-09)
    Q: Does qHPV vaccine prevent anal intraepithelial neoplasia and condylomata in men? Evidence-based answer: Yes. Quadrivalent human papillomavirus (qHPV) vaccine reduces rates of anal intraepithelial neoplasia (AIN) by 50% ...
  • Which interventions can increase breastfeeding duration? 

    Mott, Timothy; Wirtz, Mark; Nashelsky, Joan (Family Physicians Inquiries Network, 2015-09)
    Q: Which interventions can increase breastfeeding duration? Evidence-based answer: Breastfeeding support, beyond standard care, from lay people or professionals increases both short- and long-term breastfeeding duration ...
  • What’s the best test for underlying osteomyelitis in patients with diabetic foot ulcers? 

    Khodaee, Morteza; Lombardo, Daniel; Montgomery, Linda C.; Lyon, Corey; Montoya, Cathy C. (Family Physicians Inquiries Network, 2015-05)
    A: What’s the best test for underlying osteomyelitis in patients with diabetic foot ulcers? A: Magnetic resonance imaging (MRI) has a higher sensitivity and specificity (90% and 79%) than plain radiography (54% and 68%) ...
  • Do statins increase the risk of developing diabetes? 

    Parker, Kristin; Dohr, Karen; Neher, Jon O.; Kelsberg, Gary; St. Anna, Leilani (Family Physicians Inquiries Network, 2015-04)
    Q: Do statins increase the risk of developing diabetes? A: Yes. Statin therapy produces a small increase in the incidence of diabetes: one additional case per 255 patients taking statins over 4 years (strength of recommendation ...
  • What therapies alleviate symptoms of polycystic ovary syndrome? 

    Moreno, Laura; Bonnell, Ashley; Neher, Jon O.; Safranek, Sarah (Family Physicians Inquiries Network, 2015-04)
    Q: What therapies alleviate symptoms of polycystic ovary syndrome? A: Treatment of polycystic ovary syndrome (PCOS) in women not actively seeking to become pregnant is symptom-specific. Lifestyle modification (LSM) reduces ...
  • Does primary nocturnal enuresis affect childrens’ self-esteem? 

    Phung, Phuc; Kelsberg, Gary (Family Physicians Inquiries Network, 2015-04)
    Q: Does primary nocturnal enuresis affect childrens’ self-esteem? A: Yes. Children with primary nocturnal enuresis often, but not always, score about 10% lower on standardized rating scales for self esteem, or scores for ...
  • Are inhaled steroids effective for a postviral cough? 

    Insel, Kimberly; Lyon, Corey (Family Physicians Inquiries Network, 2015-03)
    Q: Are inhaled steroids effective for a postviral cough? Evidence-based answer: No. Inhaled corticosteroids (ICS) don’t improve postviral cough in adults with subacute (3-8 weeks) or chronic (>8 weeks) cough, adolescents ...

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