Browsing School of Medicine (MU) by Thesis Semester "2007 Spring"
Now showing items 1-7 of 7
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Immunity in the newborn: control by IL-13 receptor and dendritic cells
(University of Missouri--Columbia, 2007)Neonates are susceptible to microbial infections and allergic reactions due to lack of Th1 immunity. Utilization of a TCR transgenic T cell transfer system, we demonstrated that primary neonatal Th1 cells develop alongside ... -
Kinase-interacting FHA domain of kinase associated protein phosphatase: phosphopeptide interactions and NMR-detected dynamics
(University of Missouri--Columbia, 2007)FHA domains are phosphoThr recognition modules found in diverse signaling proteins. Kinase-associated protein phosphatase (KAPP) from Arabidopsis employs its FHA domain in its negative regulation of some receptor-like ... -
Lipid mediators in the development and resolution of experimental lyme arthritis
(University of Missouri--Columbia, 2007)The focus of my graduate studies was to determine the contribution of members of the eicosanoid cascade, namely the cyclooxygenase enzymes, to the regulation of experimental Lyme arthritis pathology. Using COX-2-specific ... -
The mechanism for paraquat toxicity involves oxidative stress and inflammation: a model for Parkinson's disease
(University of Missouri--Columbia, 2007)Parkinson's disease (PD) is a neurodegenerative disorder known to affect the dopaminergic neurons in the substantia nigra. Epidemiological studies have shown an increased risk of developing PD with exposure to paraquat. ... -
The role of electronic medical record in nation care delivery, development: case study on Ghana
(University of Missouri--Columbia, 2007)Electronic medical record (EMR) is not only being welcomed by health care providers as a way to improve care delivery, but also serves as a catalyst for development. The purpose of this study is to examine benefits of EMR ... -
Structural and functional studies of proline catabolic enzymes
(University of Missouri--Columbia, 2007)Catabolism is the oxidation of organic nutrients into simple end molecules to extract energy. For proline, the catabolic pathway involves two enzymes, Lproline dehydrogenase (PRODH, EC 1.5.99.8) and L-[delta]¹-pyrroline- ... -
Transcription regulation of adeno-associated viruses
(University of Missouri--Columbia, 2007)The small genome size of adeno-associated viruses demand efficient gene regulation achieved by various strategies. This research compared these strategies from AAV2, AAV5 and bovine-AAV, and found that AAV2 capsid promoter ...