Browsing School of Medicine (MU) by Thesis Semester "2008 Summer"
Now showing items 1-5 of 5
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Alcohol induced histone acetylation mediated by histone acetyl transferase GCN5 in liver
(University of Missouri--Columbia, 2008)Although several mechanisms have identified for alcoholic liver disease, at present there are no precise mechanisms for liver injury. We have observed that surrogate alcohols increases histone H3 acetylation selectively ... -
Peroxynitrite, pumps and perivascular adipose tissue : studies across the physiological spectrum
(University of Missouri--Columbia, 2008)Peroxynitrite (ONOO-) is a reactive nitrogen species produced when nitric oxide (NO) and superoxide (O2-) react. In vivo studies suggest that reactive oxygen species and perhaps peroxynitrite can influence Na,K-ATPase (Na ... -
Phenotypic modulation of vascular smooth muscle cells : evidence for a role of the G protein-coupled P2y2 receptor
(University of Missouri--Columbia, 2008)G protein-coupled receptors regulate two major functions of vascular smooth muscle cells (SMCs) - the vasomotor contractile response and the proliferative response. The contractile phenotype of SMCs has mainly been studied ... -
Phenotypically different cells in the nucleus of the solitary tract : expression of group I metabotropic glutamate receptors and activation by baroreflexes
(University of Missouri--Columbia, 2008)Modulation and integration of visceral and central afferent information occurs in the nucleus of the solitary tract (NTS). The NTS is a heterogeneous nuclear region that contains afferent terminals, interneurons, and ... -
Regulating the regulators : using CD25 depletion to enhance immune responses to a model plasmid-based vaccine
(University of Missouri--Columbia, 2008)Due to their ease of production and safety, plasmid-based vaccines have become prime candidates for both prophylactic and therapeutic human vaccination. In experimental animal models, vaccination with plasmid DNA expression ...