Browsing School of Medicine (MU) by Thesis Semester "2017 Spring"
Now showing items 1-9 of 9
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Advancements in the understanding of staphylococcal mastitis through the use of molecular tools
(University of Missouri--Columbia, 2017)The objectives of this work were: 1) to complete a whole genome sequence of a Staphylococcus chromogenes isolate that is known to persist in the mammary gland of a cow, 2) to define a genetic target that could easily and ... -
Biochemical characterization of clade B and non-B HIV-1 reverse transcriptase
(University of Missouri--Columbia, 2017)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Two classes of drugs: nucleos(t)ide reverse transcriptase inhibitors (NRTIs) and non-nucleoside RT inhibitors (NNRTIs) target HIV-1 RT, an enzyme ... -
Expression of IGF2R, IGF2, TGFß, and uPAR in a rat model of obesity /
(University of Missouri--Columbia, 2017)We tested the hypothesis that induction of obesity in lean Long Evans Tokushima Otsuka (LETO) and obesity-prone Otsuka Long Evans Tokushima Fatty (OLETF) would cause the insulin growth factor 2 receptor (IGF2R) and factors ... -
The long-term effects of a short-term study abroad experience on baccalaureate-prepared nursing students
(University of Missouri--Columbia, 2017)Cultural competency is a crucial component of baccalaureate nursing education to support patient-centered practice (Calvillo, Clark, Ballantyne, Pacquiao, Purnell, and Villarruel 2009). Studying abroad is associated with ... -
The musculoskeletal effect of exercise and soluble activin receptor type 2b in mouse models of osteogenesis imperfecta
(University of Missouri--Columbia, 2017)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Osteogenesis Imperfecta (OI) is a heritable connective tissue disorder primarily due to mutations in the type I collagen containing tissues, such as ... -
Myofibrillar regulatory mechanisms of stretch activation in mammalian striated muscle
(University of Missouri--Columbia, 2017)Stretch activation is described as a delayed increase in force after an imposed stretch. This process is essential in the flight muscles of many insects and is also observed, to some degree, in mammalian striated muscles. ... -
The Parvovirus Minute Virus of Mice modulates the DNA damage response to facilitate viral replication and a pre-mitotic cell cycle block /
(University of Missouri--Columbia, 2017)The DNA damage response (DDR) is a critical cellular network that affords cells the ability to repair DNA damage they have incurred from endogenous and exogenous sources. Recently, it has become appreciated that viruses, ... -
RNA-sequencing analysis in B-cell acute lymphoblastic leukemia reveals aberrant gene expression and splicing alterations
(University of Missouri--Columbia, 2017)Background: B-cell acute lymphoblastic leukemia (B-ALL) is a neoplasm of immature lymphoid progenitors and is the leading cause of cancer-related death in children. The majority of B-ALL cases are characterized by recurring ... -
Role of T-type Ca²⁺ channels in lymphatic pacemaking /
(University of Missouri--Columbia, 2017)Lymphatic smooth muscle (LSM) contracts spontaneously, actively returning interstitial fluid through a network of lymphatic capillaries and collecting lymphatic vessels to the great veins. Dysfunctional lymphatic contractions ...