• Diving for PURLs (July 2011) 

    Slatkoff, Susan; Mounsey, Anne L.; Jones, Kohar; Rowland, Kate (Family Physicians Inquiries Network, 2011-07)
    In the PURLs series, we attempt to select and summarize all new research studies that should change your clinical practice. Diving for PURLs will provide you with a synopsis of important studies that may not meet all of ...
  • How often should a patient with diverticulosis but a normal colonoscopy be rescreened? 

    Narciso, Philipp; Norman, Angela (Family Physicians Inquiries Network, 2009-07)
    The presence or absence of diverticulosis should not alter the follow-up interval for patients undergoing colonoscopy for the detection of colorectal cancer. (SOR C, based on expert opinion.) The frequency for colonoscopy ...
  • How useful is ultrasound to evaluate a patient with postmenopausal bleeding? 

    Hoke, Jason; Gauer, Robert (Family Physicians Inquiries Network, 2010-09)
    In a woman with postmenopausal bleeding being evaluated for endometrial carcinoma, an endometrial thickness of ≤4 mm by transvaginal ultrasound (TVU) has a negative predictive value exceeding 99%. (SOR: A, based on ...
  • Is there a role for CA-125 in the evaluation of abdominal pain? 

    Campbell, Robert J.; Nagy, Suzanne; Lagergren, Emily (Family Physicians Inquiries Network, 2009-12)
    CA-125 testing is not specific enough in the primary evaluation of abdominal pain to be clinically useful, and would have unacceptably high false-positive rates. (SOR B, based on retrospective studies and reviews.) CA-125 ...
  • Renal cell carcinoma 

    Hermiston, Jennet (Family Physicians Inquiries Network, 2009-06)
    This issue of eMedRef provides information to clinicians on the pathophysiology, diagnosis, and therapeutics of renal cell carcinoma.
  • Should we screen for ovarian cancer? 

    Wiseman, Pamela M.; Puglia, Kathleen (Family Physicians Inquiries Network, 2003-12)
    Ovarian cancer screening using pelvic examination, CA-125 serum tumor marker, transvaginal ultrasound (TVU), or any combination of tests is not recommended in average-risk women, or in women with only 1 first-degree relative ...
  • What is the appropriate management for a patient with CIN1 on colposcopy? 

    Avrich, Erin; Sulik, Sandra; Nashelsky, Joan (Family Physicians Inquiries Network, 2006-02)
    Of the different strategies available for managing cervical intraepithelial neoplasia grade 1 (CIN1), testing for high-risk subtypes of the human papillomavirus (hr-HPV) DNA at 12 months has the highest sensitivity for ...
  • What medications are effective in the treatment of anorexia/cachexia associated with advanced cancer? 

    Clayton, Suzanne; Mott, Timothy F. (Family Physicians Inquiries Network, 2013-03)
    Megestrol acetate is associated with improved appetite and weight gain in cancer-related anorexia-cachexia syndrome (CACS), but has not been shown to improve survival (SOR: A, meta-analysis). Thalidomide treatment results ...
  • Who should be routinely screened for testicular cancer? 

    White, Brett; Savard, Elizabeth Koffel; Power, David V. (Family Physicians Inquiries Network, 2009-10)
    The US Preventive Services Task Force (USPSTF) recommends against screening for testicular cancer (USPSTF “D” rating), noting there is at least moderate certainty that the service has no net benefit. The American Cancer ...