Browsing School of Medicine (MU) by Thesis Advisor "Hannink, Mark, 1958-"

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  • Characterization of PGAM5 

    Wilkins, Jordan, 1983- (University of Missouri--Columbia, 2013)
    Programmed cell death (PCD) is a naturally occurring event that is highly regulated and required for normal development. The protein phosphoglycerate mutase 5 (PGAM5) has been implicated in apoptosis, necrosis, and autophagy ...

  • Crystal structure of the kelch domain of human keap1 

    Li, Xuchu, 1976- (University of Missouri--Columbia, 2005)
    [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Nrf2-Keap1 signal transduction pathway senses oxidative stress and protects eukaryotic cells against oxidative damage and cancer. The transcription ...

  • Regulation of Nrf2 by a keap1-dependent E3 ubiquitin ligase 

    Lo, Shih-Ching, 1979- (University of Missouri--Columbia, 2007)
    Oxidative damage to biological macromolecules has been implicated in diverse pathophysiological processes, including cancer, neurodegeneration, aging and cardiovascular disease. The Nrf2 transcription factor regulates ...