• How should thyroid replacement be initiated? 

    Landis, Suzanne E.; Collins, Linda J. (Family Physicians Inquiries Network, 2004)
    Levothyroxine (LT4) should be used alone as initial replacement for patients with hypothyroidism (strength of recommendation [SOR]: A). The optimal initial dose is 1.6 μg/kg/d for healthy people aged 60 years or younger ...