• What medication best prevents migraine in children? 

    Spry, Heather; McDiarmid, Todd; Mayer, Jill Byerly (Family Physicians Inquiries Network, 2003)
    Propranolol, valproic acid, and amitriptyline are effective prophylaxis for migraine in children to varying degrees, are widely available, and have a reasonable safety profile (strength of recommendation [SOR]: B, based ...