Browsing School of Medicine (MU) by Thesis Department "Pathology and anatomical sciences (MU)"
Now showing items 1-20 of 49
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3D analysis of hip joint mobility and the evolution of locomotor abilities in miocene hominoids
(University of Missouri--Columbia, 2013)The emergence of extant ape-like locomotor behaviors has become a defining issue in reconstructing ape evolution. Suspensory positional behaviors, such as antipronograde bridging, climbing, clambering and transfer, distinguish ... -
Aberrant DNA methylationof RUN domain containing 3B in lymphoid malignancies
(University of Missouri--Columbia, 2013)Heritable changes to DNA conformation can have significant impacts on gene expression without altering the DNA sequence. The RUN domain containing 3B gene (RUNDC3B) has been shown to be differentially expressed in cancer ... -
Administration of apocynin in drinking water ameliorates transient cerebral ischemia-induced brain damage and behavioral deficits in mice
(University of Missouri--Columbia, 2012)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Acute ischemic stroke is the third leading cause of death in developed countries and the most frequent cause of permanent disability in adults worldwide. ... -
Advancements in the understanding of staphylococcal mastitis through the use of molecular tools
(University of Missouri--Columbia, 2017)The objectives of this work were: 1) to complete a whole genome sequence of a Staphylococcus chromogenes isolate that is known to persist in the mammary gland of a cow, 2) to define a genetic target that could easily and ... -
An anatomical analysis of the effects of ether anesthesia on the nerve cell
(University of Missouri--Columbia, 1915)In this investigation the writer has attempted to ascertain whether or not the anatomical changes produced by ether are similar to those produced by morphine and heat stimulation, namely slight excitation followed by ... -
The anatomical effect of certain drugs on the purkinje cells of the cerebellum
(University of Missouri--Columbia, 1912)The purpose of this series of experiments is to determine if certain drugs produce structural changes in the higher brain cells, of which the Purkinje cell is taken as a type. It is known from physiological experiments and ... -
Archosaur hip joint anatomy and its significance in body size and locomotor evolution
(University of Missouri--Columbia, 2015)Archosaurs (crocodylians, birds and their extinct relatives) underwent numerous evolutionary transitions in limb morphology and body size, reflecting a diverse suite of postural and behavioral adaptations. Among archosaurs, ... -
Avian [beta]-defensins as antimicrobial and immunomodulatory agents
(University of Missouri--Columbia, 2018)The increasing prevalence of antibiotic-resistance and lack of effective antibiotics pose a serious threat to animal health and public health. Host antimicrobial peptides (AMPs) show broad-spectrum antimicrobial activity ... -
Biological responses of ligament and tendon graft-derived fibroblasts to clinical levels of cyclic strain
(University of Missouri--Columbia, 2020)Anterior Cruciate Ligament (ACL) is one of the major ligaments in the knee. ACL injury is the partial or complete tear of the ACL usually as a consequence of a traumatic sports related injury. ACL injury commonly affects ... -
Bivalent peptide-based radioconjugates for prostate cancer imaging and potential therapy
(University of Missouri--Columbia, 2017)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Introduction: Despite decades of research, prostate cancer remains an important disease, with 1 out of 7 men diagnosed within his lifetime. In 2017, ... -
Characterization of the rat Atg16l1 gene and its role in autophagy and disease
(University of Missouri--Columbia, 2020)Crohn's disease (CD) is a potentially life-threatening inflammatory condition of the gastrointestinal tract affecting approximately 1.6 million Americans. Previous studies confirm the important role of genetics in IBD. ... -
Comparative biomechanics of cranial kinesis in reptiles
(University of Missouri--Columbia, 2020)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] "The vertebrate skull is a composite organ made from structures that arise from different developmental, evolutionary and biomechanical phenomena. Of ... -
Comprehensive profiling of micro RNA in human papillomavirus-associated squamous cell carcinoma of the head and neck
(University of Missouri--Columbia, 2014) -
Computational modeling, ontogeny, and biomechanics of cranial forces in Alligator mississippiensis
(University of Missouri--Columbia, 2015)3D computational modeling offers researchers tools to investigate forces in the skull during feeding and other behaviors. The American alligator and other crocodylians generate the highest bite forces among vertebrates, ... -
Cytological study of the development of the functional activity of nerve cells in foetal and infantile animals
(University of Missouri--Columbia, 1913)Morphological changes corresponding to functional activity have been found by numerous investigators. The purpose of this investigation was in the first place to determine, if possible, at what period functional activity ... -
Defining recurrent laryngeal nerve injury in a mouse model for regenerative therapeutic investigations
(University of Missouri--Columbia, 2019)Injury of the recurrent laryngeal nerve (RLN), a branch of the vagus nerve, results in ipsilateral vocal fold (VF) paralysis that contributes to dysphagia, dysphonia, and dyspnea (i.e., swallow, vocal, and respiratory ... -
Deregulation of the notch signaling pathway N B-cell chronic lymphocytic leukemia
(University of Missouri--Columbia, 2011)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] B-cell Chronic Lymphocytic Leukemia (B-CLL) is the most common hematological malignancy in United States[1], characterized by CD5+ B-lymphocytes in ... -
Development of post-traumatic osteoarthritis models to evaluate the effects of impact injury on joint health for clinical disease treatment and prevention
(University of Missouri--Columbia, 2013)Osteoarthritis is one of the most common, debilitating, musculoskeletal diseases in the world. Currently, there is no cure. It is well-known that a traumatic, joint injury increases the risk of developing post-traumatic ... -
The development of the administration of public health and safety, Kansas City, Missouri
(University of Missouri--Columbia, 1907)As indicated by the title, this is a study of the development of administration in the field of Public Health and Safety in Kansas City. Mr. Fairlie in his Municipal Administration includes within this field Economic ... -
Development of translational models for intervertebral disc degeneration using a comparative approach for canine and human patients
(University of Missouri--Columbia, 2020)Intervertebral discs (IVDs) are unique musculoskeletal tissues within functional spinal unit organs comprising the spinal column that distribute loads and allow complex movements for vertebrates. IVD degeneration has been ...