Browsing Department of Medical Pharmacology and Physiology (MU) by Thesis Advisor "Davis, George Edward, 1957-"
Now showing items 1-4 of 4
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Molecular control of endothelial lumen formation by Rho GTPases in three dimensional collagen matrices
(University of Missouri--Columbia, 2008)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Rho GTPases regulate a diverse spectrum of cellular functions involved in vascular morphogenesis. Here, we show that Cdc42 and Rac1 play a key role ... -
Molecular control of endothelial tube formation from single and aggregated cells by lumen signalling complexes that contain MT1-MMP and CDC42 in 3D collagen matrices
(University of Missouri--Columbia, 2010)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The first blood vessels to form in the embryo are generated by vasculogenesis. New insight into vasculogenesis in mammals is emerging from studies of ... -
Molecular mechanisms controlling endothelial cell-pericyte tube coassembly during vascular morphogenesis
(University of Missouri--Columbia, 2010)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] From the onset the goal of this thesis work was to determine the role that a novel class of growth factors, i.e. hematopoietic cytokines, was playing ... -
Molecular mechanisms of tumor invasion in three-dimensional collagen matrices
(University of Missouri--Columbia, 2007)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Cancer remains a significant cause of morbidity and mortality worldwide, and invasion and metastasis substantially contribute to poor prognosis and ...