Which patients with gastroesophageal reflux disease (GERD) should have esophagogastroduoudenoscopy (EGD)?

Abstract

No evidence was identified that provides a basis for determining whether EGD leads to improved outcomes in patients with GERD. However, patients with GERD referred for elective EGD who were found to have Barrett's esophagus were more likely to have symptoms for more than 1 year than patients who did not have Barrett's esophagus. Patients with esophageal adenocarcinoma were more likely to have frequent, severe, or longer duration of GERD symptoms. The calculated odds ratios (OR) for esophageal adenocarcinoma increased with increasing frequency, severity, or duration of GERD symptoms, independently or in combination.