• In patients with a previous CVA, do antioxidants protect against subsequent stroke? 

    Spencer, Donald C.; Meadows, Susan E. (Family Physicians Inquiries Network, 2002-11)
    Most recent randomized controlled clinical trials have not found a benefit in antioxidants (vitamin C, vitamin E, and/or beta-carotene) for preventing cardiovascular disease, including stroke. These recent clinical studies ...
  • What are the most effective interventions to reduce childhood obesity? 

    Hill, John C.; Smith, Peter C.; Meadows, Susan E. (Family Physicians Inquiries Network, 2002-10)
    Efforts to increase physical activity or decrease sedentary activities have shown some short-term benefit, and adding dietary changes may be more effective. Aiming interventions at parents, intensive family therapy, ...
  • What is the best therapy for constipation in infants? 

    Ellis, Mark R.; Meadows, Susan E. (Family Physicians Inquiries Network, 2002-08)
    The best treatment for minor, self-limited constipation (infant dyschezia) may be observation and parental education about its benign nature. (Grade of recommendation: D, expert opinion.) For cases requiring treatment, ...
  • What is the initial approach to the treatment of shoulder pain? 

    Weismantel, David; Abbott, Cathleen M.; Meadows, Susan E. (Family Physicians Inquiries Network, 2002-01)
    There is some limited evidence supporting the use of nonsteroidal anti-inflammatory drugs (NSAIDs) in the initial treatment of shoulder pain. There is no evidence in support of most other therapies, including intra-articular ...
  • What is the target for low-density lipoprotein cholesterol in patients with heart disease? 

    Stevermer, James J.; Meadows, Susan E. (Family Physicians Inquiries Network, 2002-10)
    Large published randomized controlled trials (RCTs) show that pravastatin and simvastatin are well-tolerated and reduce major coronary events such as death, myocardial infarction, and revascularization by about 25%. The ...
  • What levels of cholesterol should be treated for primary prevention? 

    Seaton, Terry L.; Meadows, Susan E. (Family Physicians Inquiries Network, 2002-05)
    The levels of cholesterol that should be treated for primary prevention are based on low-density lipoprotein cholesterol (LDL-C) levels of > 100 mg/dL to > 190 mg/dL and vary according to whether the patient's risk is ...
  • When should acute nonvenereal conjunctivitis be treated with topical antibiotics? 

    Kane, Kevin Y.; Meadows, Susan E.; Ellis, Mark R. (Family Physicians Inquiries Network, 2002-04)
    Children with suspected or culture-proven acute nonvenereal bacterial conjunctivitis should be treated with topical antibiotics, which hastens clinical and microbiological remission and may prevent potentially serious ...
  • When should patients with asymptomatic aortic stenosis be evaluated for valve replacement? 

    Colen, Michelle; Lindbloom, Erik; Meadows, Susan E. (Family Physicians Inquiries Network, 2002-09)
    For patients whose echocardiograms show advanced calcification of the aortic valves, a jet velocity of > 4.0 m/s, or a progression in jet velocity of 0.3m/s/year; and for patients who have an abnormal exercise response or ...