• Do antioxidants (vitamins C, E) improve outcomes in patients with coronary artery disease? 

    Bloom, O. Josh; McDiarmid, Todd; Scoville, Caryn (Family Physicians Inquiries Network, 2002-11)
    Antioxidant supplements of vitamins E and C do not reduce cardiovascular death in people with coronary artery disease. Vitamin E supplementation, in a variety of doses, does not decrease the incidence of cardiovascular or ...
  • What are the indications for tonsillectomy in children? 

    Neill, Richard A.; Scoville, Caryn (Family Physicians Inquiries Network, 2002-04)
    Tonsillectomy with or without adenoidectomy is minimally effective when combined with tympanostomy tube placement in preventing recurrent otitis media in the 3 years following surgery. The risks of surgery must be weighed ...
  • What are the treatment options for SSRI-related sexual dysfunction? 

    Sturpe, Deborah A.; Mertens, Marsha K.; Scoville, Caryn (Family Physicians Inquiries Network, 2002-08)
    Substituting bupropion, nefazodone, or mirtazapine is beneficial. (Grade of recommendation: B, randomized controlled trials [RCTs].) Augmentation therapy with amantadine, bupropion, and buspirone is no better than placebo. ...
  • What is the best treatment for impacted cerumen? 

    Wilson, Stephen A.; Scoville, Caryn (Family Physicians Inquiries Network, 2002-02)
    Docusate sodium given 15 minutes before irrigation is most effective for facilitating cerumen removal during a single office visit. (Grade of recommendation: B, based on head-to-head trials that lacked irrigationonly arms.) ...
  • What is the best way to evaluate acute diarrhea? 

    Montgomery, Lynda; Scoville, Caryn (Family Physicians Inquiries Network, 2002-06)
    Limited evidence delineates the relative probabilities of causes of acute diarrhea, typically defined as a diarrheal disease lasting 14 days or fewer, in the developed world. Viruses (rotavirus, Norwalk, and other enteric ...