What nonhormonal therapies are effective for postmenopausal vasomotor symptoms?
No Thumbnail Available
Authors
Meeting name
Sponsors
Date
Journal Title
Format
Article
Abstract
Regular exercise may reduce vasomotor symptoms of menopause (strength of recommendation [SOR]: C--single observational study). Soy products/isoflavones, either through diet or supplementation, may reduce the incidence of hot flushes (SOR: D--inconsistent results of randomized trials). Clonidine, as an oral or transdermal preparation, reduces hot flushes (SOR: A--randomized clinical trials), as does gabapentin (SOR: A-- single randomized clinical trial). In cancer patients who have had surgical menopause, selective serotonin reuptake inhibitors and megestrol (Megase) have been effective in reducing hot flushes (SOR: A; B for extrapolation to the general population). Other therapies--including Bellergal (a combination of belladonna, ergotamine, and phenobarbital), methyldopa, evening primrose oil, maiquan, flaxseed, ginseng, and topical wild yam extract--have not been effective. Black cohosh may be effective, but the evidence for this is of poor quality (SOR: C).
Table of Contents
DOI
PubMed ID
Degree
Thesis Department
Rights
OpenAccess.
License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.