Who should have colposcopy?

Abstract

Colposcopy is the preferred test in the work-up of patients with abnormal cervical cytology: • Low-grade squamous intraepithelial lesion (LSIL): mild dysplasia • High-grade squamous intraepithelial lesion (HSIL): moderate to severe dysplasia. • Atypical squamous cells of undetermined significance (ASC-US) with high-risk human papillo-mavirus (HPV) DNA • Atypical squamous cells, cannot rule out HSIL (ASC-H) • Atypical glandular cells (AGC) • Adenocarcinoma in situ (AIS). Colposcopy is also recommended for patients with symptoms suggestive of cervical cancer (abnormal appearance of the cervix, persistent and undiagnosed vaginal discharge or bleeding) regardless of cytology results, and in the follow-up of patients previously treated for cervical dysplasia (Grade of Recommendation: B). Colposcopy is not recommended for routine cervical cancer screening.