Does tight control of blood glucose in pregnant women with diabetes improve neonatal outcomes?

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Does tight control of blood glucose in pregnant women with diabetes improve neonatal outcomes?

Please use this identifier to cite or link to this item: http://hdl.handle.net/10355/3057

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Title: Does tight control of blood glucose in pregnant women with diabetes improve neonatal outcomes?
Author: Fotinos, Charissa; Dodson, Sherry
Keywords: neonatal hypoglycemia
type 1 diabetes mellitus
impaired glucose tolerance
Date: 2004-10
Publisher: Family Physicians Inquiries Network
Citation: Journal of Family Practice, 53(10) 2004: 838-841.
Abstract: In pregnant women with preexisting type 1 diabetes mellitus, maintaining near-normal blood glucose levels decreases the rate of major congenital anomalies (defined as those causing death or a serious handicap necessitating surgical correction or medical treatment). Prolonged preconception control of blood sugar to near normal levels reduces the rate of major congenital anomalies close to those seen in women without diabetes (strength of recommendation [SOR]: A, based on prospective cohort studies and randomized controlled trial [RCT]). Intensive management reduces the risk of congenital anomalies more than conventional therapy, and lowers the risk of neonatal hypoglycemia (SOR: B, based on RCT). Very tight control does not reduce clinically significant neonatal morbidity but does increase the risk of maternal hypoglycemia (SOR: B, based on a systematic review).
URI: http://hdl.handle.net/10355/3057

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